Winslow99.cpp

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///////////////////////////////////////////////////////////////////////////////
//
// File: Winslow99.cpp
//
// For more information, please see: http://www.nektar.info
//
// The MIT License
//
// Copyright (c) 2006 Division of Applied Mathematics, Brown University (USA),
// Department of Aeronautics, Imperial College London (UK), and Scientific
// Computing and Imaging Institute, University of Utah (USA).
//
// Permission is hereby granted, free of charge, to any person obtaining a
// copy of this software and associated documentation files (the "Software"),
// to deal in the Software without restriction, including without limitation
// the rights to use, copy, modify, merge, publish, distribute, sublicense,
// and/or sell copies of the Software, and to permit persons to whom the
// Software is furnished to do so, subject to the following conditions:
//
// The above copyright notice and this permission notice shall be included
// in all copies or substantial portions of the Software.
//
// THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS
// OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
// FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL
// THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
// LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING
// FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER
// DEALINGS IN THE SOFTWARE.
//
// Description: Winslow 1999 cell model
//
///////////////////////////////////////////////////////////////////////////////
 
#include <iostream>
#include <string>
// #include <LibUtilities/BasicUtils/Vmath.hpp>
#include <CardiacEPSolver/CellModels/Winslow99.h>
 
namespace Nektar
{
std::string Winslow99::className =
    GetCellModelFactory().RegisterCreatorFunction(
        "Winslow99", Winslow99::create, "Winslow 1999 cell model.");
 
/**
 *
 */
Winslow99::Winslow99(const LibUtilities::SessionReaderSharedPtr &pSession,
                     const MultiRegions::ExpListSharedPtr &pField)
    : CellModel(pSession, pField)
{
    m_nvar = 33;
    m_gates.push_back(1);
    m_gates.push_back(2);
    m_gates.push_back(3);
    m_gates.push_back(4);
    m_gates.push_back(5);
    m_gates.push_back(6);
    m_gates.push_back(7);
    m_concentrations.push_back(8);
    m_concentrations.push_back(9);
    m_concentrations.push_back(10);
    m_concentrations.push_back(11);
    m_concentrations.push_back(12);
    m_concentrations.push_back(13);
    m_concentrations.push_back(14);
    m_concentrations.push_back(15);
    m_concentrations.push_back(16);
    m_concentrations.push_back(17);
    m_concentrations.push_back(18);
    m_concentrations.push_back(19);
    m_gates.push_back(20);
    m_concentrations.push_back(21);
    m_concentrations.push_back(22);
    m_concentrations.push_back(23);
    m_concentrations.push_back(24);
    m_concentrations.push_back(25);
    m_concentrations.push_back(26);
    m_concentrations.push_back(27);
    m_concentrations.push_back(28);
    m_concentrations.push_back(29);
    m_concentrations.push_back(30);
    m_concentrations.push_back(31);
    m_concentrations.push_back(32);
}
 
void Winslow99::v_Update(
    const Array<OneD, const Array<OneD, NekDouble>> &inarray,
    Array<OneD, Array<OneD, NekDouble>> &outarray,
    [[maybe_unused]] const NekDouble time)
{
    for (size_t i = 0; i < m_nq; ++i)
    {
 
        // Inputs:
        // Time units: millisecond
        NekDouble var_chaste_interface__membrane__V = inarray[0][i];
        // Units: millivolt; Initial value: -96.1638
        NekDouble var_chaste_interface__fast_sodium_current_m_gate__m =
            inarray[1][i];
        // Units: dimensionless; Initial value: 0.0328302
        NekDouble var_chaste_interface__fast_sodium_current_h_gate__h =
            inarray[2][i];
        // Units: dimensionless; Initial value: 0.988354
        NekDouble var_chaste_interface__fast_sodium_current_j_gate__j =
            inarray[3][i];
        // Units: dimensionless; Initial value: 0.99254
        NekDouble
            var_chaste_interface__rapid_activating_delayed_rectifiyer_K_current_X_kr_gate__X_kr =
                inarray[4][i];
        // Units: dimensionless; Initial value: 0.51
        NekDouble
            var_chaste_interface__slow_activating_delayed_rectifiyer_K_current_X_ks_gate__X_ks =
                inarray[5][i];
        // Units: dimensionless; Initial value: 0.264
        NekDouble
            var_chaste_interface__transient_outward_potassium_current_X_to1_gate__X_to1 =
                inarray[6][i];
        // Units: dimensionless; Initial value: 2.63
        NekDouble
            var_chaste_interface__transient_outward_potassium_current_Y_to1_gate__Y_to1 =
                inarray[7][i];
        // Units: dimensionless; Initial value: 0.99
        NekDouble var_chaste_interface__L_type_Ca_current__O = inarray[8][i];
        // Units: dimensionless; Initial value: 9.84546e-21
        NekDouble var_chaste_interface__L_type_Ca_current__O_Ca = inarray[9][i];
        // Units: dimensionless; Initial value: 0
        NekDouble var_chaste_interface__L_type_Ca_current__C0 = inarray[10][i];
        // Units: dimensionless; Initial value: 0.997208
        NekDouble var_chaste_interface__L_type_Ca_current__C1 = inarray[11][i];
        // Units: dimensionless; Initial value: 6.38897e-5
        NekDouble var_chaste_interface__L_type_Ca_current__C2 = inarray[12][i];
        // Units: dimensionless; Initial value: 1.535e-9
        NekDouble var_chaste_interface__L_type_Ca_current__C3 = inarray[13][i];
        // Units: dimensionless; Initial value: 1.63909e-14
        NekDouble var_chaste_interface__L_type_Ca_current__C4 = inarray[14][i];
        // Units: dimensionless; Initial value: 6.56337e-20
        NekDouble var_chaste_interface__L_type_Ca_current__C_Ca0 =
            inarray[15][i];
        // Units: dimensionless; Initial value: 0.00272826
        NekDouble var_chaste_interface__L_type_Ca_current__C_Ca1 =
            inarray[16][i];
        // Units: dimensionless; Initial value: 6.99215e-7
        NekDouble var_chaste_interface__L_type_Ca_current__C_Ca2 =
            inarray[17][i];
        // Units: dimensionless; Initial value: 6.71989e-11
        NekDouble var_chaste_interface__L_type_Ca_current__C_Ca3 =
            inarray[18][i];
        // Units: dimensionless; Initial value: 2.87031e-15
        NekDouble var_chaste_interface__L_type_Ca_current__C_Ca4 =
            inarray[19][i];
        // Units: dimensionless; Initial value: 4.59752e-20
        NekDouble var_chaste_interface__L_type_Ca_current_y_gate__y =
            inarray[20][i];
        // Units: dimensionless; Initial value: 0.798
        NekDouble var_chaste_interface__RyR_channel__P_O1 = inarray[21][i];
        // Units: dimensionless; Initial value: 0
        NekDouble var_chaste_interface__RyR_channel__P_O2 = inarray[22][i];
        // Units: dimensionless; Initial value: 0
        NekDouble var_chaste_interface__RyR_channel__P_C1 = inarray[23][i];
        // Units: dimensionless; Initial value: 0.47
        NekDouble var_chaste_interface__RyR_channel__P_C2 = inarray[24][i];
        // Units: dimensionless; Initial value: 0.53
        NekDouble var_chaste_interface__intracellular_Ca_fluxes__HTRPNCa =
            inarray[25][i];
        // Units: millimolar; Initial value: 0.98
        NekDouble var_chaste_interface__intracellular_Ca_fluxes__LTRPNCa =
            inarray[26][i];
        // Units: millimolar; Initial value: 0.078
        NekDouble var_chaste_interface__intracellular_ion_concentrations__Nai =
            inarray[27][i];
        // Units: millimolar; Initial value: 10
        NekDouble var_chaste_interface__intracellular_ion_concentrations__Cai =
            inarray[28][i];
        // Units: millimolar; Initial value: 0.00008
        NekDouble var_chaste_interface__intracellular_ion_concentrations__Ki =
            inarray[29][i];
        // Units: millimolar; Initial value: 157.8
        NekDouble
            var_chaste_interface__intracellular_ion_concentrations__Ca_ss =
                inarray[30][i];
        // Units: millimolar; Initial value: 0.00011
        NekDouble
            var_chaste_interface__intracellular_ion_concentrations__Ca_JSR =
                inarray[31][i];
        // Units: millimolar; Initial value: 0.257
        NekDouble
            var_chaste_interface__intracellular_ion_concentrations__Ca_NSR =
                inarray[32][i];
        // Units: millimolar; Initial value: 0.257
 
        // Mathematics
        NekDouble d_dt_chaste_interface__membrane__V;
        const NekDouble var_membrane__R = 8.314472;   // joule_per_mole_kelvin
        const NekDouble var_membrane__T = 310.0;      // kelvin
        const NekDouble var_membrane__F = 96.4853415; // coulomb_per_millimole
        const NekDouble var_fast_sodium_current__j =
            var_chaste_interface__fast_sodium_current_j_gate__j; // dimensionless
        const NekDouble var_fast_sodium_current__h =
            var_chaste_interface__fast_sodium_current_h_gate__h; // dimensionless
        const NekDouble var_fast_sodium_current__g_Na =
            12.8; // milliS_per_microF
        const NekDouble var_fast_sodium_current__m =
            var_chaste_interface__fast_sodium_current_m_gate__m; // dimensionless
        const NekDouble var_fast_sodium_current__V =
            var_chaste_interface__membrane__V; // millivolt
        const NekDouble var_fast_sodium_current__R =
            var_membrane__R; // joule_per_mole_kelvin
        const NekDouble var_fast_sodium_current__F =
            var_membrane__F; // coulomb_per_millimole
        const NekDouble var_standard_ionic_concentrations__Nao =
            138.0; // millimolar
        const NekDouble var_fast_sodium_current__Nao =
            var_standard_ionic_concentrations__Nao; // millimolar
        const NekDouble var_fast_sodium_current__Nai =
            var_chaste_interface__intracellular_ion_concentrations__Nai; // millimolar
        const NekDouble var_fast_sodium_current__T = var_membrane__T; // kelvin
        const NekDouble var_fast_sodium_current__E_Na =
            ((var_fast_sodium_current__R * var_fast_sodium_current__T) /
             var_fast_sodium_current__F) *
            log(var_fast_sodium_current__Nao /
                var_fast_sodium_current__Nai); // millivolt
        const NekDouble var_fast_sodium_current__i_Na =
            var_fast_sodium_current__g_Na *
            pow(var_fast_sodium_current__m, 3.0) * var_fast_sodium_current__h *
            var_fast_sodium_current__j *
            (var_fast_sodium_current__V -
             var_fast_sodium_current__E_Na); // microA_per_microF
        const NekDouble var_L_type_Ca_current__O =
            var_chaste_interface__L_type_Ca_current__O; // dimensionless
        const NekDouble var_L_type_Ca_current__F =
            var_membrane__F; // coulomb_per_millimole
        const NekDouble var_L_type_Ca_current__P_Ca =
            0.0003125; // cm_per_second
        const NekDouble var_standard_ionic_concentrations__Cao =
            2.0; // millimolar
        const NekDouble var_L_type_Ca_current__Cao =
            var_standard_ionic_concentrations__Cao; // millimolar
        const NekDouble var_L_type_Ca_current__V =
            var_chaste_interface__membrane__V;                      // millivolt
        const NekDouble var_L_type_Ca_current__T = var_membrane__T; // kelvin
        const NekDouble var_L_type_Ca_current__R =
            var_membrane__R; // joule_per_mole_kelvin
        const NekDouble var_L_type_Ca_current__i_Ca_max =
            ((((var_L_type_Ca_current__P_Ca / (1.0 * 1.0)) * 4.0 *
               var_L_type_Ca_current__V * pow(var_L_type_Ca_current__F, 2.0) *
               1000.0) /
              (var_L_type_Ca_current__R * var_L_type_Ca_current__T)) *
             ((0.001 *
               exp((2.0 * var_L_type_Ca_current__V * var_L_type_Ca_current__F) /
                   (var_L_type_Ca_current__R * var_L_type_Ca_current__T))) -
              (0.341 * var_L_type_Ca_current__Cao))) /
            (exp((2.0 * var_L_type_Ca_current__V * var_L_type_Ca_current__F) /
                 (var_L_type_Ca_current__R * var_L_type_Ca_current__T)) -
             1.0); // microA_per_microF
        const NekDouble var_L_type_Ca_current__y =
            var_chaste_interface__L_type_Ca_current_y_gate__y; // dimensionless
        const NekDouble var_L_type_Ca_current__O_Ca =
            var_chaste_interface__L_type_Ca_current__O_Ca; // dimensionless
        const NekDouble var_L_type_Ca_current__i_Ca =
            var_L_type_Ca_current__i_Ca_max * var_L_type_Ca_current__y *
            (var_L_type_Ca_current__O +
             var_L_type_Ca_current__O_Ca); // microA_per_microF
        const NekDouble var_L_type_Ca_current__P_K = 5.79e-07; // cm_per_second
        const NekDouble var_L_type_Ca_current__i_Ca_half =
            -0.265; // microA_per_microF
        const NekDouble var_L_type_Ca_current__p_prime_k =
            var_L_type_Ca_current__P_K /
            (1.0 + (var_L_type_Ca_current__i_Ca_max /
                    var_L_type_Ca_current__i_Ca_half)); // cm_per_second
        const NekDouble var_standard_ionic_concentrations__Ko =
            4.0; // millimolar
        const NekDouble var_L_type_Ca_current__Ko =
            var_standard_ionic_concentrations__Ko; // millimolar
        const NekDouble var_L_type_Ca_current__Ki =
            var_chaste_interface__intracellular_ion_concentrations__Ki; // millimolar
        const NekDouble var_L_type_Ca_current__i_Ca_K =
            ((((var_L_type_Ca_current__p_prime_k / (1.0 * 1.0)) *
               var_L_type_Ca_current__y *
               (var_L_type_Ca_current__O + var_L_type_Ca_current__O_Ca) *
               var_L_type_Ca_current__V * pow(var_L_type_Ca_current__F, 2.0)) /
              (var_L_type_Ca_current__R * var_L_type_Ca_current__T)) *
             ((var_L_type_Ca_current__Ki *
               exp((var_L_type_Ca_current__V * var_L_type_Ca_current__F) /
                   (var_L_type_Ca_current__R * var_L_type_Ca_current__T))) -
              var_L_type_Ca_current__Ko)) /
            (exp((var_L_type_Ca_current__V * var_L_type_Ca_current__F) /
                 (var_L_type_Ca_current__R * var_L_type_Ca_current__T)) -
             1.0); // microA_per_microF
        const NekDouble var_rapid_activating_delayed_rectifiyer_K_current__Ko =
            var_standard_ionic_concentrations__Ko; // millimolar
        const NekDouble
            var_rapid_activating_delayed_rectifiyer_K_current__f_Ko =
                sqrt(var_rapid_activating_delayed_rectifiyer_K_current__Ko /
                     4.0); // dimensionless
        const NekDouble var_rapid_activating_delayed_rectifiyer_K_current__Ki =
            var_chaste_interface__intracellular_ion_concentrations__Ki; // millimolar
        const NekDouble var_rapid_activating_delayed_rectifiyer_K_current__R =
            var_membrane__R; // joule_per_mole_kelvin
        const NekDouble var_rapid_activating_delayed_rectifiyer_K_current__F =
            var_membrane__F; // coulomb_per_millimole
        const NekDouble var_rapid_activating_delayed_rectifiyer_K_current__T =
            var_membrane__T; // kelvin
        const NekDouble var_rapid_activating_delayed_rectifiyer_K_current__E_K =
            ((var_rapid_activating_delayed_rectifiyer_K_current__R *
              var_rapid_activating_delayed_rectifiyer_K_current__T) /
             var_rapid_activating_delayed_rectifiyer_K_current__F) *
            log(var_rapid_activating_delayed_rectifiyer_K_current__Ko /
                var_rapid_activating_delayed_rectifiyer_K_current__Ki); // millivolt
        const NekDouble var_rapid_activating_delayed_rectifiyer_K_current__V =
            var_chaste_interface__membrane__V; // millivolt
        const NekDouble var_rapid_activating_delayed_rectifiyer_K_current__R_V =
            1.0 /
            (1.0 +
             (1.4945 *
              exp(0.0446 *
                  var_rapid_activating_delayed_rectifiyer_K_current__V))); // dimensionless
        const NekDouble var_rapid_activating_delayed_rectifiyer_K_current__X_kr =
            var_chaste_interface__rapid_activating_delayed_rectifiyer_K_current_X_kr_gate__X_kr; // dimensionless
        const NekDouble
            var_rapid_activating_delayed_rectifiyer_K_current__g_Kr =
                0.0034; // milliS_per_microF
        const NekDouble var_rapid_activating_delayed_rectifiyer_K_current__i_Kr =
            var_rapid_activating_delayed_rectifiyer_K_current__g_Kr *
            var_rapid_activating_delayed_rectifiyer_K_current__f_Ko *
            var_rapid_activating_delayed_rectifiyer_K_current__R_V *
            var_rapid_activating_delayed_rectifiyer_K_current__X_kr *
            (var_rapid_activating_delayed_rectifiyer_K_current__V -
             var_rapid_activating_delayed_rectifiyer_K_current__E_K); // microA_per_microF
        const NekDouble var_slow_activating_delayed_rectifiyer_K_current__g_Ks =
            0.0027134; // milliS_per_microF
        const NekDouble var_slow_activating_delayed_rectifiyer_K_current__Ko =
            var_standard_ionic_concentrations__Ko; // millimolar
        const NekDouble var_slow_activating_delayed_rectifiyer_K_current__Nao =
            var_standard_ionic_concentrations__Nao; // millimolar
        const NekDouble var_slow_activating_delayed_rectifiyer_K_current__Ki =
            var_chaste_interface__intracellular_ion_concentrations__Ki; // millimolar
        const NekDouble var_slow_activating_delayed_rectifiyer_K_current__Nai =
            var_chaste_interface__intracellular_ion_concentrations__Nai; // millimolar
        const NekDouble var_slow_activating_delayed_rectifiyer_K_current__R =
            var_membrane__R; // joule_per_mole_kelvin
        const NekDouble var_slow_activating_delayed_rectifiyer_K_current__F =
            var_membrane__F; // coulomb_per_millimole
        const NekDouble var_slow_activating_delayed_rectifiyer_K_current__T =
            var_membrane__T; // kelvin
        const NekDouble var_slow_activating_delayed_rectifiyer_K_current__E_Ks =
            ((var_slow_activating_delayed_rectifiyer_K_current__R *
              var_slow_activating_delayed_rectifiyer_K_current__T) /
             var_slow_activating_delayed_rectifiyer_K_current__F) *
            log((var_slow_activating_delayed_rectifiyer_K_current__Ko +
                 (0.01833 *
                  var_slow_activating_delayed_rectifiyer_K_current__Nao)) /
                (var_slow_activating_delayed_rectifiyer_K_current__Ki +
                 (0.01833 *
                  var_slow_activating_delayed_rectifiyer_K_current__Nai))); // millivolt
        const NekDouble var_slow_activating_delayed_rectifiyer_K_current__V =
            var_chaste_interface__membrane__V; // millivolt
        const NekDouble var_slow_activating_delayed_rectifiyer_K_current__X_ks =
            var_chaste_interface__slow_activating_delayed_rectifiyer_K_current_X_ks_gate__X_ks; // dimensionless
        const NekDouble var_slow_activating_delayed_rectifiyer_K_current__i_Ks =
            var_slow_activating_delayed_rectifiyer_K_current__g_Ks *
            pow(var_slow_activating_delayed_rectifiyer_K_current__X_ks, 2.0) *
            (var_slow_activating_delayed_rectifiyer_K_current__V -
             var_slow_activating_delayed_rectifiyer_K_current__E_Ks); // microA_per_microF
        const NekDouble var_transient_outward_potassium_current__X_to1 =
            var_chaste_interface__transient_outward_potassium_current_X_to1_gate__X_to1; // dimensionless
        const NekDouble var_transient_outward_potassium_current__Y_to1 =
            var_chaste_interface__transient_outward_potassium_current_Y_to1_gate__Y_to1; // dimensionless
        const NekDouble var_transient_outward_potassium_current__g_to1 =
            0.23815; // milliS_per_microF
        const NekDouble var_transient_outward_potassium_current__E_K =
            var_rapid_activating_delayed_rectifiyer_K_current__E_K; // millivolt
        const NekDouble var_transient_outward_potassium_current__V =
            var_chaste_interface__membrane__V; // millivolt
        const NekDouble var_transient_outward_potassium_current__i_to1 =
            var_transient_outward_potassium_current__g_to1 *
            var_transient_outward_potassium_current__X_to1 *
            var_transient_outward_potassium_current__Y_to1 *
            (var_transient_outward_potassium_current__V -
             var_transient_outward_potassium_current__E_K); // microA_per_microF
        const NekDouble var_time_independent_potassium_current__Ko =
            var_standard_ionic_concentrations__Ko; // millimolar
        const NekDouble var_time_independent_potassium_current__E_K =
            var_rapid_activating_delayed_rectifiyer_K_current__E_K; // millivolt
        const NekDouble var_time_independent_potassium_current__F =
            var_membrane__F; // coulomb_per_millimole
        const NekDouble var_time_independent_potassium_current_K1_gate__F =
            var_time_independent_potassium_current__F; // coulomb_per_millimole
        const NekDouble var_time_independent_potassium_current__V =
            var_chaste_interface__membrane__V; // millivolt
        const NekDouble var_time_independent_potassium_current_K1_gate__V =
            var_time_independent_potassium_current__V; // millivolt
        const NekDouble var_time_independent_potassium_current__T =
            var_membrane__T; // kelvin
        const NekDouble var_time_independent_potassium_current_K1_gate__T =
            var_time_independent_potassium_current__T; // kelvin
        const NekDouble var_time_independent_potassium_current_K1_gate__E_K =
            var_time_independent_potassium_current__E_K; // millivolt
        const NekDouble var_time_independent_potassium_current__R =
            var_membrane__R; // joule_per_mole_kelvin
        const NekDouble var_time_independent_potassium_current_K1_gate__R =
            var_time_independent_potassium_current__R; // joule_per_mole_kelvin
        const NekDouble
            var_time_independent_potassium_current_K1_gate__K1_infinity_V =
                1.0 /
                (2.0 +
                 exp(((1.5 *
                       var_time_independent_potassium_current_K1_gate__F) /
                      (var_time_independent_potassium_current_K1_gate__R *
                       var_time_independent_potassium_current_K1_gate__T)) *
                     (var_time_independent_potassium_current_K1_gate__V -
                      var_time_independent_potassium_current_K1_gate__E_K))); // dimensionless
        const NekDouble var_time_independent_potassium_current__K1_infinity_V =
            var_time_independent_potassium_current_K1_gate__K1_infinity_V; // dimensionless
        const NekDouble var_time_independent_potassium_current__g_K1 =
            2.8; // milliS_per_microF
        const NekDouble var_time_independent_potassium_current__K_mK1 =
            13.0; // millimolar
        const NekDouble var_time_independent_potassium_current__i_K1 =
            ((var_time_independent_potassium_current__g_K1 *
              var_time_independent_potassium_current__K1_infinity_V *
              var_time_independent_potassium_current__Ko) /
             (var_time_independent_potassium_current__Ko +
              var_time_independent_potassium_current__K_mK1)) *
            (var_time_independent_potassium_current__V -
             var_time_independent_potassium_current__E_K); // microA_per_microF
        const NekDouble var_plateau_potassium_current__g_Kp =
            0.002216; // milliS_per_microF
        const NekDouble var_plateau_potassium_current__V =
            var_chaste_interface__membrane__V; // millivolt
        const NekDouble var_plateau_potassium_current_Kp_gate__V =
            var_plateau_potassium_current__V; // millivolt
        const NekDouble var_plateau_potassium_current_Kp_gate__Kp_V =
            1.0 /
            (1.0 + exp((7.488 - var_plateau_potassium_current_Kp_gate__V) /
                       5.98)); // dimensionless
        const NekDouble var_plateau_potassium_current__Kp_V =
            var_plateau_potassium_current_Kp_gate__Kp_V; // dimensionless
        const NekDouble var_plateau_potassium_current__E_K =
            var_rapid_activating_delayed_rectifiyer_K_current__E_K; // millivolt
        const NekDouble var_plateau_potassium_current__i_Kp =
            var_plateau_potassium_current__g_Kp *
            var_plateau_potassium_current__Kp_V *
            (var_plateau_potassium_current__V -
             var_plateau_potassium_current__E_K); // microA_per_microF
        const NekDouble var_Na_Ca_exchanger__Nao =
            var_standard_ionic_concentrations__Nao;        // millimolar
        const NekDouble var_Na_Ca_exchanger__K_sat = 0.2;  // dimensionless
        const NekDouble var_Na_Ca_exchanger__K_mNa = 87.5; // millimolar
        const NekDouble var_Na_Ca_exchanger__Nai =
            var_chaste_interface__intracellular_ion_concentrations__Nai; // millimolar
        const NekDouble var_Na_Ca_exchanger__K_NaCa = 0.3; // microA_per_microF
        const NekDouble var_Na_Ca_exchanger__V =
            var_chaste_interface__membrane__V;                    // millivolt
        const NekDouble var_Na_Ca_exchanger__T = var_membrane__T; // kelvin
        const NekDouble var_Na_Ca_exchanger__Cao =
            var_standard_ionic_concentrations__Cao;        // millimolar
        const NekDouble var_Na_Ca_exchanger__eta   = 0.35; // dimensionless
        const NekDouble var_Na_Ca_exchanger__K_mCa = 1.38; // millimolar
        const NekDouble var_Na_Ca_exchanger__F =
            var_membrane__F; // coulomb_per_millimole
        const NekDouble var_Na_Ca_exchanger__R =
            var_membrane__R; // joule_per_mole_kelvin
        const NekDouble var_Na_Ca_exchanger__Cai =
            var_chaste_interface__intracellular_ion_concentrations__Cai; // millimolar
        const NekDouble var_Na_Ca_exchanger__i_NaCa =
            ((var_Na_Ca_exchanger__K_NaCa * 5000.0) /
             ((pow(var_Na_Ca_exchanger__K_mNa, 3.0) +
               pow(var_Na_Ca_exchanger__Nao, 3.0)) *
              (var_Na_Ca_exchanger__K_mCa + var_Na_Ca_exchanger__Cao) *
              (1.0 +
               (var_Na_Ca_exchanger__K_sat *
                exp(((var_Na_Ca_exchanger__eta - 1.0) * var_Na_Ca_exchanger__V *
                     var_Na_Ca_exchanger__F) /
                    (var_Na_Ca_exchanger__R * var_Na_Ca_exchanger__T)))))) *
            ((exp((var_Na_Ca_exchanger__eta * var_Na_Ca_exchanger__V *
                   var_Na_Ca_exchanger__F) /
                  (var_Na_Ca_exchanger__R * var_Na_Ca_exchanger__T)) *
              pow(var_Na_Ca_exchanger__Nai, 3.0) * var_Na_Ca_exchanger__Cao) -
             (exp(((var_Na_Ca_exchanger__eta - 1.0) * var_Na_Ca_exchanger__V *
                   var_Na_Ca_exchanger__F) /
                  (var_Na_Ca_exchanger__R * var_Na_Ca_exchanger__T)) *
              pow(var_Na_Ca_exchanger__Nao, 3.0) *
              var_Na_Ca_exchanger__Cai)); // microA_per_microF
        const NekDouble var_sodium_potassium_pump__Ko =
            var_standard_ionic_concentrations__Ko;                // millimolar
        const NekDouble var_sodium_potassium_pump__K_mNai = 10.0; // millimolar
        const NekDouble var_sodium_potassium_pump__Nai =
            var_chaste_interface__intracellular_ion_concentrations__Nai; // millimolar
        const NekDouble var_sodium_potassium_pump__V =
            var_chaste_interface__membrane__V; // millivolt
        const NekDouble var_sodium_potassium_pump__F =
            var_membrane__F; // coulomb_per_millimole
        const NekDouble var_sodium_potassium_pump__T =
            var_membrane__T; // kelvin
        const NekDouble var_sodium_potassium_pump__Nao =
            var_standard_ionic_concentrations__Nao; // millimolar
        const NekDouble var_sodium_potassium_pump__sigma =
            (1.0 / 7.0) *
            (exp(var_sodium_potassium_pump__Nao / 67.3) - 1.0); // dimensionless
        const NekDouble var_sodium_potassium_pump__R =
            var_membrane__R; // joule_per_mole_kelvin
        const NekDouble var_sodium_potassium_pump__f_NaK =
            1.0 / (1.0 +
                   (0.1245 * exp(((-0.1) * var_sodium_potassium_pump__V *
                                  var_sodium_potassium_pump__F) /
                                 (var_sodium_potassium_pump__R *
                                  var_sodium_potassium_pump__T))) +
                   (0.0365 * var_sodium_potassium_pump__sigma *
                    exp(((-var_sodium_potassium_pump__V) *
                         var_sodium_potassium_pump__F) /
                        (var_sodium_potassium_pump__R *
                         var_sodium_potassium_pump__T)))); // dimensionless
        const NekDouble var_sodium_potassium_pump__I_NaK =
            0.693; // microA_per_microF
        const NekDouble var_sodium_potassium_pump__K_mKo = 1.5; // millimolar
        const NekDouble var_sodium_potassium_pump__i_NaK =
            (((var_sodium_potassium_pump__I_NaK *
               var_sodium_potassium_pump__f_NaK) /
              (1.0 + pow(var_sodium_potassium_pump__K_mNai /
                             var_sodium_potassium_pump__Nai,
                         1.5))) *
             var_sodium_potassium_pump__Ko) /
            (var_sodium_potassium_pump__Ko +
             var_sodium_potassium_pump__K_mKo); // microA_per_microF
        const NekDouble var_sarcolemmal_calcium_pump__I_pCa =
            0.05; // microA_per_microF
        const NekDouble var_sarcolemmal_calcium_pump__Cai =
            var_chaste_interface__intracellular_ion_concentrations__Cai; // millimolar
        const NekDouble var_sarcolemmal_calcium_pump__K_mpCa =
            5e-05; // millimolar
        const NekDouble var_sarcolemmal_calcium_pump__i_p_Ca =
            (var_sarcolemmal_calcium_pump__I_pCa *
             var_sarcolemmal_calcium_pump__Cai) /
            (var_sarcolemmal_calcium_pump__K_mpCa +
             var_sarcolemmal_calcium_pump__Cai); // microA_per_microF
        const NekDouble var_calcium_background_current__R =
            var_membrane__R; // joule_per_mole_kelvin
        const NekDouble var_calcium_background_current__Cai =
            var_chaste_interface__intracellular_ion_concentrations__Cai; // millimolar
        const NekDouble var_calcium_background_current__F =
            var_membrane__F; // coulomb_per_millimole
        const NekDouble var_calcium_background_current__T =
            var_membrane__T; // kelvin
        const NekDouble var_calcium_background_current__Cao =
            var_standard_ionic_concentrations__Cao; // millimolar
        const NekDouble var_calcium_background_current__E_Ca =
            ((var_calcium_background_current__R *
              var_calcium_background_current__T) /
             (2.0 * var_calcium_background_current__F)) *
            log(var_calcium_background_current__Cao /
                var_calcium_background_current__Cai); // millivolt
        const NekDouble var_calcium_background_current__g_Cab =
            0.0003842; // milliS_per_microF
        const NekDouble var_calcium_background_current__V =
            var_chaste_interface__membrane__V; // millivolt
        const NekDouble var_calcium_background_current__i_Ca_b =
            var_calcium_background_current__g_Cab *
            (var_calcium_background_current__V -
             var_calcium_background_current__E_Ca); // microA_per_microF
        const NekDouble var_sodium_background_current__g_Nab =
            0.0031; // milliS_per_microF
        const NekDouble var_sodium_background_current__V =
            var_chaste_interface__membrane__V; // millivolt
        const NekDouble var_sodium_background_current__E_Na =
            var_fast_sodium_current__E_Na; // millivolt
        const NekDouble var_sodium_background_current__i_Na_b =
            var_sodium_background_current__g_Nab *
            (var_sodium_background_current__V -
             var_sodium_background_current__E_Na); // microA_per_microF
        const NekDouble var_fast_sodium_current_m_gate__V =
            var_fast_sodium_current__V; // millivolt
        const NekDouble var_fast_sodium_current_m_gate__beta_m =
            80.0 *
            exp((-var_fast_sodium_current_m_gate__V) / 11.0); // per_second
        const NekDouble var_fast_sodium_current_m_gate__E0_m =
            var_fast_sodium_current_m_gate__V + 47.13; // millivolt
        const NekDouble var_fast_sodium_current_m_gate__alpha_m =
            (fabs(var_fast_sodium_current_m_gate__E0_m) < 1e-05)
                ? (1000.0 /
                   (0.1 - (0.005 * var_fast_sodium_current_m_gate__E0_m)))
                : ((320.0 * var_fast_sodium_current_m_gate__E0_m) /
                   (1.0 -
                    exp((-0.1) *
                        var_fast_sodium_current_m_gate__E0_m))); // per_second
        const NekDouble var_fast_sodium_current_m_gate__m =
            var_fast_sodium_current__m; // dimensionless
        const NekDouble
            var_fast_sodium_current_m_gate__d_m_d_environment__time =
                (var_fast_sodium_current_m_gate__V >= (-90.0))
                    ? ((var_fast_sodium_current_m_gate__alpha_m *
                        (1.0 - var_fast_sodium_current_m_gate__m)) -
                       (var_fast_sodium_current_m_gate__beta_m *
                        var_fast_sodium_current_m_gate__m))
                    : 0.0; // per_second
        const NekDouble
            var_fast_sodium_current__fast_sodium_current_m_gate__d_m_d_environment__time =
                var_fast_sodium_current_m_gate__d_m_d_environment__time; // per_second
        const NekDouble var_fast_sodium_current_h_gate__V =
            var_fast_sodium_current__V; // millivolt
        const NekDouble var_fast_sodium_current_h_gate__beta_h =
            (var_fast_sodium_current_h_gate__V < (-40.0))
                ? ((3560.0 * exp(0.079 * var_fast_sodium_current_h_gate__V)) +
                   (310000.0 * exp(0.35 * var_fast_sodium_current_h_gate__V)))
                : (1000.0 /
                   (0.13 *
                    (1.0 + exp((var_fast_sodium_current_h_gate__V + 10.66) /
                               (-11.1))))); // per_second
        const NekDouble var_fast_sodium_current_h_gate__alpha_h =
            (var_fast_sodium_current_h_gate__V < (-40.0))
                ? (135.0 *
                   exp((80.0 + var_fast_sodium_current_h_gate__V) / (-6.8)))
                : 0.0; // per_second
        const NekDouble var_fast_sodium_current_h_gate__h =
            var_fast_sodium_current__h; // dimensionless
        const NekDouble
            var_fast_sodium_current_h_gate__d_h_d_environment__time =
                (var_fast_sodium_current_h_gate__alpha_h *
                 (1.0 - var_fast_sodium_current_h_gate__h)) -
                (var_fast_sodium_current_h_gate__beta_h *
                 var_fast_sodium_current_h_gate__h); // per_second
        const NekDouble
            var_fast_sodium_current__fast_sodium_current_h_gate__d_h_d_environment__time =
                var_fast_sodium_current_h_gate__d_h_d_environment__time; // per_second
        const NekDouble var_fast_sodium_current_j_gate__V =
            var_fast_sodium_current__V; // millivolt
        const NekDouble var_fast_sodium_current_j_gate__alpha_j =
            (var_fast_sodium_current_j_gate__V < (-40.0))
                ? ((1000.0 *
                    (-((127140.0 *
                        exp(0.2444 * var_fast_sodium_current_j_gate__V)) +
                       (3.474e-05 *
                        exp((-0.04391) * var_fast_sodium_current_j_gate__V)))) *
                    (var_fast_sodium_current_j_gate__V + 37.78)) /
                   (1.0 +
                    exp(0.311 * (var_fast_sodium_current_j_gate__V + 79.23))))
                : 0.0; // per_second
        const NekDouble var_fast_sodium_current_j_gate__beta_j =
            (var_fast_sodium_current_j_gate__V < (-40.0))
                ? ((121.2 *
                    exp((-0.01052) * var_fast_sodium_current_j_gate__V)) /
                   (1.0 + exp((-0.1378) *
                              (var_fast_sodium_current_j_gate__V + 40.14))))
                : ((300.0 *
                    exp((-2.535e-07) * var_fast_sodium_current_j_gate__V)) /
                   (1.0 + exp((-0.1) * (var_fast_sodium_current_j_gate__V +
                                        32.0)))); // per_second
        const NekDouble var_fast_sodium_current_j_gate__j =
            var_fast_sodium_current__j; // dimensionless
        const NekDouble
            var_fast_sodium_current_j_gate__d_j_d_environment__time =
                (var_fast_sodium_current_j_gate__alpha_j *
                 (1.0 - var_fast_sodium_current_j_gate__j)) -
                (var_fast_sodium_current_j_gate__beta_j *
                 var_fast_sodium_current_j_gate__j); // per_second
        const NekDouble
            var_fast_sodium_current__fast_sodium_current_j_gate__d_j_d_environment__time =
                var_fast_sodium_current_j_gate__d_j_d_environment__time; // per_second
        const NekDouble
            var_rapid_activating_delayed_rectifiyer_K_current_X_kr_gate__tau_factor =
                1.0; // dimensionless
        const NekDouble
            var_rapid_activating_delayed_rectifiyer_K_current_X_kr_gate__V =
                var_rapid_activating_delayed_rectifiyer_K_current__V; // millivolt
        const NekDouble
            var_rapid_activating_delayed_rectifiyer_K_current_X_kr_gate__K21 = exp(
                (-7.677) -
                (0.0128 *
                 var_rapid_activating_delayed_rectifiyer_K_current_X_kr_gate__V)); // dimensionless
        const NekDouble
            var_rapid_activating_delayed_rectifiyer_K_current_X_kr_gate__K12 = exp(
                (-5.495) +
                (0.1691 *
                 var_rapid_activating_delayed_rectifiyer_K_current_X_kr_gate__V)); // dimensionless
        const NekDouble var_rapid_activating_delayed_rectifiyer_K_current_X_kr_gate__tau_X_kr =
            (0.001 /
             (var_rapid_activating_delayed_rectifiyer_K_current_X_kr_gate__K12 +
              var_rapid_activating_delayed_rectifiyer_K_current_X_kr_gate__K21)) +
            (var_rapid_activating_delayed_rectifiyer_K_current_X_kr_gate__tau_factor *
             0.027); // second
        const NekDouble
            var_rapid_activating_delayed_rectifiyer_K_current_X_kr_gate__X_kr =
                var_rapid_activating_delayed_rectifiyer_K_current__X_kr; // dimensionless
        const NekDouble
            var_rapid_activating_delayed_rectifiyer_K_current_X_kr_gate__X_kr_inf =
                var_rapid_activating_delayed_rectifiyer_K_current_X_kr_gate__K12 /
                (var_rapid_activating_delayed_rectifiyer_K_current_X_kr_gate__K12 +
                 var_rapid_activating_delayed_rectifiyer_K_current_X_kr_gate__K21); // dimensionless
        const NekDouble var_rapid_activating_delayed_rectifiyer_K_current_X_kr_gate__d_X_kr_d_environment__time =
            (var_rapid_activating_delayed_rectifiyer_K_current_X_kr_gate__X_kr_inf -
             var_rapid_activating_delayed_rectifiyer_K_current_X_kr_gate__X_kr) /
            var_rapid_activating_delayed_rectifiyer_K_current_X_kr_gate__tau_X_kr; // per_second
        const NekDouble
            var_rapid_activating_delayed_rectifiyer_K_current__rapid_activating_delayed_rectifiyer_K_current_X_kr_gate__d_X_kr_d_environment__time =
                var_rapid_activating_delayed_rectifiyer_K_current_X_kr_gate__d_X_kr_d_environment__time; // per_second
        const NekDouble
            var_slow_activating_delayed_rectifiyer_K_current_X_ks_gate__V =
                var_slow_activating_delayed_rectifiyer_K_current__V; // millivolt
        const NekDouble var_slow_activating_delayed_rectifiyer_K_current_X_ks_gate__tau_X_ks =
            0.001 /
            (((7.19e-05 *
               (var_slow_activating_delayed_rectifiyer_K_current_X_ks_gate__V -
                10.0)) /
              (1.0 -
               exp((-0.148) *
                   (var_slow_activating_delayed_rectifiyer_K_current_X_ks_gate__V -
                    10.0)))) +
             ((0.000131 *
               (var_slow_activating_delayed_rectifiyer_K_current_X_ks_gate__V -
                10.0)) /
              (exp(0.0687 *
                   (var_slow_activating_delayed_rectifiyer_K_current_X_ks_gate__V -
                    10.0)) -
               1.0))); // second
        const NekDouble
            var_slow_activating_delayed_rectifiyer_K_current_X_ks_gate__X_ks_infinity =
                1.0 /
                (1.0 +
                 exp((-(var_slow_activating_delayed_rectifiyer_K_current_X_ks_gate__V -
                        24.7)) /
                     13.6)); // dimensionless
        const NekDouble
            var_slow_activating_delayed_rectifiyer_K_current_X_ks_gate__X_ks =
                var_slow_activating_delayed_rectifiyer_K_current__X_ks; // dimensionless
        const NekDouble var_slow_activating_delayed_rectifiyer_K_current_X_ks_gate__d_X_ks_d_environment__time =
            (var_slow_activating_delayed_rectifiyer_K_current_X_ks_gate__X_ks_infinity -
             var_slow_activating_delayed_rectifiyer_K_current_X_ks_gate__X_ks) /
            var_slow_activating_delayed_rectifiyer_K_current_X_ks_gate__tau_X_ks; // per_second
        const NekDouble
            var_slow_activating_delayed_rectifiyer_K_current__slow_activating_delayed_rectifiyer_K_current_X_ks_gate__d_X_ks_d_environment__time =
                var_slow_activating_delayed_rectifiyer_K_current_X_ks_gate__d_X_ks_d_environment__time; // per_second
        const NekDouble var_transient_outward_potassium_current_X_to1_gate__V =
            var_transient_outward_potassium_current__V; // millivolt
        const NekDouble
            var_transient_outward_potassium_current_X_to1_gate__alpha_X_to1 =
                45.16 *
                exp(0.03577 *
                    var_transient_outward_potassium_current_X_to1_gate__V); // per_second
        const NekDouble
            var_transient_outward_potassium_current_X_to1_gate__X_to1 =
                var_transient_outward_potassium_current__X_to1; // dimensionless
        const NekDouble
            var_transient_outward_potassium_current_X_to1_gate__beta_X_to1 =
                98.9 *
                exp((-0.06237) *
                    var_transient_outward_potassium_current_X_to1_gate__V); // per_second
        const NekDouble
            var_transient_outward_potassium_current_X_to1_gate__d_X_to1_d_environment__time =
                (var_transient_outward_potassium_current_X_to1_gate__alpha_X_to1 *
                 (1.0 -
                  var_transient_outward_potassium_current_X_to1_gate__X_to1)) -
                (var_transient_outward_potassium_current_X_to1_gate__beta_X_to1 *
                 var_transient_outward_potassium_current_X_to1_gate__X_to1); // per_second
        const NekDouble
            var_transient_outward_potassium_current__transient_outward_potassium_current_X_to1_gate__d_X_to1_d_environment__time =
                var_transient_outward_potassium_current_X_to1_gate__d_X_to1_d_environment__time; // per_second
        const NekDouble var_transient_outward_potassium_current_Y_to1_gate__V =
            var_transient_outward_potassium_current__V; // millivolt
        const NekDouble
            var_transient_outward_potassium_current_Y_to1_gate__alpha_Y_to1 =
                (5.415 *
                 exp((-(var_transient_outward_potassium_current_Y_to1_gate__V +
                        33.5)) /
                     5.0)) /
                (1.0 +
                 (0.051335 *
                  exp((-(var_transient_outward_potassium_current_Y_to1_gate__V +
                         33.5)) /
                      5.0))); // per_second
        const NekDouble
            var_transient_outward_potassium_current_Y_to1_gate__Y_to1 =
                var_transient_outward_potassium_current__Y_to1; // dimensionless
        const NekDouble
            var_transient_outward_potassium_current_Y_to1_gate__beta_Y_to1 =
                (5.415 *
                 exp((var_transient_outward_potassium_current_Y_to1_gate__V +
                      33.5) /
                     5.0)) /
                (1.0 +
                 (0.051335 *
                  exp((var_transient_outward_potassium_current_Y_to1_gate__V +
                       33.5) /
                      5.0))); // per_second
        const NekDouble
            var_transient_outward_potassium_current_Y_to1_gate__d_Y_to1_d_environment__time =
                (var_transient_outward_potassium_current_Y_to1_gate__alpha_Y_to1 *
                 (1.0 -
                  var_transient_outward_potassium_current_Y_to1_gate__Y_to1)) -
                (var_transient_outward_potassium_current_Y_to1_gate__beta_Y_to1 *
                 var_transient_outward_potassium_current_Y_to1_gate__Y_to1); // per_second
        const NekDouble
            var_transient_outward_potassium_current__transient_outward_potassium_current_Y_to1_gate__d_Y_to1_d_environment__time =
                var_transient_outward_potassium_current_Y_to1_gate__d_Y_to1_d_environment__time; // per_second
        const NekDouble var_L_type_Ca_current__alpha =
            400.0 * exp((var_L_type_Ca_current__V + 2.0) / 10.0); // per_second
        const NekDouble var_L_type_Ca_current__beta =
            50.0 *
            exp((-(var_L_type_Ca_current__V + 2.0)) / 13.0); // per_second
        const NekDouble var_L_type_Ca_current__Ca_ss =
            var_chaste_interface__intracellular_ion_concentrations__Ca_ss; // millimolar
        const NekDouble var_L_type_Ca_current__gamma =
            (103.75 * var_L_type_Ca_current__Ca_ss) / 1.0; // per_second
        const NekDouble var_L_type_Ca_current__a = 2.0;    // dimensionless
        const NekDouble var_L_type_Ca_current__alpha_a =
            var_L_type_Ca_current__alpha *
            var_L_type_Ca_current__a;                   // per_second
        const NekDouble var_L_type_Ca_current__b = 2.0; // dimensionless
        const NekDouble var_L_type_Ca_current__beta_b =
            var_L_type_Ca_current__beta /
            var_L_type_Ca_current__b;                           // per_second
        const NekDouble var_L_type_Ca_current__g      = 2000.0; // per_second
        const NekDouble var_L_type_Ca_current__f      = 300.0;  // per_second
        const NekDouble var_L_type_Ca_current__gprime = 7000.0; // per_second
        const NekDouble var_L_type_Ca_current__fprime = 7.0;    // per_second
        const NekDouble var_L_type_Ca_current__omega  = 10.0;   // per_second
        const NekDouble var_L_type_Ca_current__C0 =
            var_chaste_interface__L_type_Ca_current__C0; // dimensionless
        const NekDouble var_L_type_Ca_current__C1 =
            var_chaste_interface__L_type_Ca_current__C1; // dimensionless
        const NekDouble var_L_type_Ca_current__C2 =
            var_chaste_interface__L_type_Ca_current__C2; // dimensionless
        const NekDouble var_L_type_Ca_current__C3 =
            var_chaste_interface__L_type_Ca_current__C3; // dimensionless
        const NekDouble var_L_type_Ca_current__C4 =
            var_chaste_interface__L_type_Ca_current__C4; // dimensionless
        const NekDouble var_L_type_Ca_current__C_Ca0 =
            var_chaste_interface__L_type_Ca_current__C_Ca0; // dimensionless
        const NekDouble var_L_type_Ca_current__C_Ca1 =
            var_chaste_interface__L_type_Ca_current__C_Ca1; // dimensionless
        const NekDouble var_L_type_Ca_current__C_Ca2 =
            var_chaste_interface__L_type_Ca_current__C_Ca2; // dimensionless
        const NekDouble var_L_type_Ca_current__C_Ca3 =
            var_chaste_interface__L_type_Ca_current__C_Ca3; // dimensionless
        const NekDouble var_L_type_Ca_current__C_Ca4 =
            var_chaste_interface__L_type_Ca_current__C_Ca4; // dimensionless
        const NekDouble var_L_type_Ca_current__d_O_d_environment__time =
            (var_L_type_Ca_current__f * var_L_type_Ca_current__C4) -
            (var_L_type_Ca_current__g * var_L_type_Ca_current__O); // per_second
        const NekDouble var_L_type_Ca_current__d_O_Ca_d_environment__time =
            (var_L_type_Ca_current__fprime * var_L_type_Ca_current__C_Ca4) -
            (var_L_type_Ca_current__gprime *
             var_L_type_Ca_current__O_Ca); // per_second
        const NekDouble var_L_type_Ca_current__d_C0_d_environment__time =
            ((var_L_type_Ca_current__beta * var_L_type_Ca_current__C1) +
             (var_L_type_Ca_current__omega * var_L_type_Ca_current__C_Ca0)) -
            (((4.0 * var_L_type_Ca_current__alpha) +
              var_L_type_Ca_current__gamma) *
             var_L_type_Ca_current__C0); // per_second
        const NekDouble var_L_type_Ca_current__d_C1_d_environment__time =
            ((4.0 * var_L_type_Ca_current__alpha * var_L_type_Ca_current__C0) +
             (2.0 * var_L_type_Ca_current__beta * var_L_type_Ca_current__C2) +
             ((var_L_type_Ca_current__omega / var_L_type_Ca_current__b) *
              var_L_type_Ca_current__C_Ca1)) -
            ((var_L_type_Ca_current__beta +
              (3.0 * var_L_type_Ca_current__alpha) +
              (var_L_type_Ca_current__gamma * var_L_type_Ca_current__a)) *
             var_L_type_Ca_current__C1); // per_second
        const NekDouble var_L_type_Ca_current__d_C2_d_environment__time =
            ((3.0 * var_L_type_Ca_current__alpha * var_L_type_Ca_current__C1) +
             (3.0 * var_L_type_Ca_current__beta * var_L_type_Ca_current__C3) +
             ((var_L_type_Ca_current__omega /
               pow(var_L_type_Ca_current__b, 2.0)) *
              var_L_type_Ca_current__C_Ca2)) -
            (((var_L_type_Ca_current__beta * 2.0) +
              (2.0 * var_L_type_Ca_current__alpha) +
              (var_L_type_Ca_current__gamma *
               pow(var_L_type_Ca_current__a, 2.0))) *
             var_L_type_Ca_current__C2); // per_second
        const NekDouble var_L_type_Ca_current__d_C3_d_environment__time =
            ((2.0 * var_L_type_Ca_current__alpha * var_L_type_Ca_current__C2) +
             (4.0 * var_L_type_Ca_current__beta * var_L_type_Ca_current__C4) +
             ((var_L_type_Ca_current__omega /
               pow(var_L_type_Ca_current__b, 3.0)) *
              var_L_type_Ca_current__C_Ca3)) -
            (((var_L_type_Ca_current__beta * 3.0) +
              var_L_type_Ca_current__alpha +
              (var_L_type_Ca_current__gamma *
               pow(var_L_type_Ca_current__a, 3.0))) *
             var_L_type_Ca_current__C3); // per_second
        const NekDouble var_L_type_Ca_current__d_C4_d_environment__time =
            ((var_L_type_Ca_current__alpha * var_L_type_Ca_current__C3) +
             (var_L_type_Ca_current__g * var_L_type_Ca_current__O) +
             ((var_L_type_Ca_current__omega /
               pow(var_L_type_Ca_current__b, 4.0)) *
              var_L_type_Ca_current__C_Ca4)) -
            (((var_L_type_Ca_current__beta * 4.0) + var_L_type_Ca_current__f +
              (var_L_type_Ca_current__gamma *
               pow(var_L_type_Ca_current__a, 4.0))) *
             var_L_type_Ca_current__C4); // per_second
        const NekDouble var_L_type_Ca_current__d_C_Ca0_d_environment__time =
            ((var_L_type_Ca_current__beta_b * var_L_type_Ca_current__C_Ca1) +
             (var_L_type_Ca_current__gamma * var_L_type_Ca_current__C0)) -
            (((4.0 * var_L_type_Ca_current__alpha_a) +
              var_L_type_Ca_current__omega) *
             var_L_type_Ca_current__C_Ca0); // per_second
        const NekDouble var_L_type_Ca_current__d_C_Ca1_d_environment__time =
            ((4.0 * var_L_type_Ca_current__alpha_a *
              var_L_type_Ca_current__C_Ca0) +
             (2.0 * var_L_type_Ca_current__beta_b *
              var_L_type_Ca_current__C_Ca2) +
             (var_L_type_Ca_current__gamma * var_L_type_Ca_current__a *
              var_L_type_Ca_current__C1)) -
            ((var_L_type_Ca_current__beta_b +
              (3.0 * var_L_type_Ca_current__alpha_a) +
              (var_L_type_Ca_current__omega / var_L_type_Ca_current__b)) *
             var_L_type_Ca_current__C_Ca1); // per_second
        const NekDouble var_L_type_Ca_current__d_C_Ca2_d_environment__time =
            ((3.0 * var_L_type_Ca_current__alpha_a *
              var_L_type_Ca_current__C_Ca1) +
             (3.0 * var_L_type_Ca_current__beta_b *
              var_L_type_Ca_current__C_Ca3) +
             (var_L_type_Ca_current__gamma *
              pow(var_L_type_Ca_current__a, 2.0) * var_L_type_Ca_current__C2)) -
            (((var_L_type_Ca_current__beta_b * 2.0) +
              (2.0 * var_L_type_Ca_current__alpha_a) +
              (var_L_type_Ca_current__omega /
               pow(var_L_type_Ca_current__b, 2.0))) *
             var_L_type_Ca_current__C_Ca2); // per_second
        const NekDouble var_L_type_Ca_current__d_C_Ca3_d_environment__time =
            ((2.0 * var_L_type_Ca_current__alpha_a *
              var_L_type_Ca_current__C_Ca2) +
             (4.0 * var_L_type_Ca_current__beta_b *
              var_L_type_Ca_current__C_Ca4) +
             (var_L_type_Ca_current__gamma *
              pow(var_L_type_Ca_current__a, 3.0) * var_L_type_Ca_current__C3)) -
            (((var_L_type_Ca_current__beta_b * 3.0) +
              var_L_type_Ca_current__alpha_a +
              (var_L_type_Ca_current__omega /
               pow(var_L_type_Ca_current__b, 3.0))) *
             var_L_type_Ca_current__C_Ca3); // per_second
        const NekDouble var_L_type_Ca_current__d_C_Ca4_d_environment__time =
            ((var_L_type_Ca_current__alpha_a * var_L_type_Ca_current__C_Ca3) +
             (var_L_type_Ca_current__gprime * var_L_type_Ca_current__O_Ca) +
             (var_L_type_Ca_current__gamma *
              pow(var_L_type_Ca_current__a, 4.0) * var_L_type_Ca_current__C4)) -
            (((var_L_type_Ca_current__beta_b * 4.0) +
              var_L_type_Ca_current__fprime +
              (var_L_type_Ca_current__omega /
               pow(var_L_type_Ca_current__b, 4.0))) *
             var_L_type_Ca_current__C_Ca4); // per_second
        const NekDouble var_L_type_Ca_current_y_gate__y =
            var_L_type_Ca_current__y; // dimensionless
        const NekDouble var_L_type_Ca_current_y_gate__V =
            var_L_type_Ca_current__V; // millivolt
        const NekDouble var_L_type_Ca_current_y_gate__y_infinity =
            (0.8 /
             (1.0 + exp((var_L_type_Ca_current_y_gate__V + 12.5) / 5.0))) +
            0.2; // dimensionless
        const NekDouble var_L_type_Ca_current_y_gate__tau_y =
            (20.0 +
             (600.0 /
              (1.0 + exp((var_L_type_Ca_current_y_gate__V + 20.0) / 9.5)))) /
            1000.0; // second
        const NekDouble var_L_type_Ca_current_y_gate__d_y_d_environment__time =
            (var_L_type_Ca_current_y_gate__y_infinity -
             var_L_type_Ca_current_y_gate__y) /
            var_L_type_Ca_current_y_gate__tau_y; // per_second
        const NekDouble
            var_L_type_Ca_current__L_type_Ca_current_y_gate__d_y_d_environment__time =
                var_L_type_Ca_current_y_gate__d_y_d_environment__time; // per_second
        const NekDouble var_RyR_channel__P_O2 =
            var_chaste_interface__RyR_channel__P_O2; // dimensionless
        const NekDouble var_RyR_channel__Ca_ss =
            var_chaste_interface__intracellular_ion_concentrations__Ca_ss; // millimolar
        const NekDouble var_RyR_channel__P_O1 =
            var_chaste_interface__RyR_channel__P_O1;  // dimensionless
        const NekDouble var_RyR_channel__v1 = 1800.0; // per_second
        const NekDouble var_RyR_channel__Ca_JSR =
            var_chaste_interface__intracellular_ion_concentrations__Ca_JSR; // millimolar
        const NekDouble var_RyR_channel__J_rel =
            var_RyR_channel__v1 *
            (var_RyR_channel__P_O1 + var_RyR_channel__P_O2) *
            (var_RyR_channel__Ca_JSR -
             var_RyR_channel__Ca_ss); // millimolar_per_second
        const NekDouble var_RyR_channel__k_a_plus =
            1.215e+13; // millimolar4_per_second
        const NekDouble var_RyR_channel__k_a_minus = 576.0; // per_second
        const NekDouble var_RyR_channel__k_b_plus =
            4050000000.0; // millimolar3_per_second
        const NekDouble var_RyR_channel__k_b_minus = 1930.0; // per_second
        const NekDouble var_RyR_channel__k_c_plus  = 100.0;  // per_second
        const NekDouble var_RyR_channel__k_c_minus = 0.8;    // per_second
        const NekDouble var_RyR_channel__P_C1 =
            var_chaste_interface__RyR_channel__P_C1; // dimensionless
        const NekDouble var_RyR_channel__P_C2 =
            var_chaste_interface__RyR_channel__P_C2; // dimensionless
        const NekDouble var_RyR_channel__n = 4.0;    // dimensionless
        const NekDouble var_RyR_channel__m = 3.0;    // dimensionless
        const NekDouble var_RyR_channel__d_P_O1_d_environment__time =
            ((var_RyR_channel__k_a_plus *
              pow(var_RyR_channel__Ca_ss, var_RyR_channel__n) *
              var_RyR_channel__P_C1) -
             ((var_RyR_channel__k_a_minus * var_RyR_channel__P_O1) +
              (var_RyR_channel__k_b_plus *
               pow(var_RyR_channel__Ca_ss, var_RyR_channel__m) *
               var_RyR_channel__P_O1) +
              (var_RyR_channel__k_c_plus * var_RyR_channel__P_O1))) +
            (var_RyR_channel__k_b_minus * var_RyR_channel__P_O2) +
            (var_RyR_channel__k_c_minus * var_RyR_channel__P_C2); // per_second
        const NekDouble var_RyR_channel__d_P_O2_d_environment__time =
            (var_RyR_channel__k_b_plus *
             pow(var_RyR_channel__Ca_ss, var_RyR_channel__m) *
             var_RyR_channel__P_O1) -
            (var_RyR_channel__k_b_minus * var_RyR_channel__P_O2); // per_second
        const NekDouble var_RyR_channel__d_P_C1_d_environment__time =
            ((-var_RyR_channel__k_a_plus) *
             pow(var_RyR_channel__Ca_ss, var_RyR_channel__n) *
             var_RyR_channel__P_C1) +
            (var_RyR_channel__k_a_minus * var_RyR_channel__P_O1); // per_second
        const NekDouble var_RyR_channel__d_P_C2_d_environment__time =
            (var_RyR_channel__k_c_plus * var_RyR_channel__P_O1) -
            (var_RyR_channel__k_c_minus * var_RyR_channel__P_C2); // per_second
        const NekDouble var_SERCA2a_pump__Cai =
            var_chaste_interface__intracellular_ion_concentrations__Cai; // millimolar
        const NekDouble var_SERCA2a_pump__N_fb = 1.2;      // dimensionless
        const NekDouble var_SERCA2a_pump__K_fb = 0.000168; // millimolar
        const NekDouble var_SERCA2a_pump__fb =
            pow(var_SERCA2a_pump__Cai / var_SERCA2a_pump__K_fb,
                var_SERCA2a_pump__N_fb); // dimensionless
        const NekDouble var_SERCA2a_pump__Vmaxf =
            0.0813;                                   // millimolar_per_second
        const NekDouble var_SERCA2a_pump__K_SR = 1.0; // dimensionless
        const NekDouble var_SERCA2a_pump__Ca_NSR =
            var_chaste_interface__intracellular_ion_concentrations__Ca_NSR; // millimolar
        const NekDouble var_SERCA2a_pump__K_rb = 3.29; // millimolar
        const NekDouble var_SERCA2a_pump__N_rb = 1.0;  // dimensionless
        const NekDouble var_SERCA2a_pump__rb =
            pow(var_SERCA2a_pump__Ca_NSR / var_SERCA2a_pump__K_rb,
                var_SERCA2a_pump__N_rb); // dimensionless
        const NekDouble var_SERCA2a_pump__Vmaxr =
            0.318; // millimolar_per_second
        const NekDouble var_SERCA2a_pump__J_up =
            (var_SERCA2a_pump__K_SR *
             ((var_SERCA2a_pump__Vmaxf * var_SERCA2a_pump__fb) -
              (var_SERCA2a_pump__Vmaxr * var_SERCA2a_pump__rb))) /
            (1.0 + var_SERCA2a_pump__fb +
             var_SERCA2a_pump__rb); // millimolar_per_second
        const NekDouble var_intracellular_Ca_fluxes__Ca_NSR =
            var_chaste_interface__intracellular_ion_concentrations__Ca_NSR; // millimolar
        const NekDouble var_intracellular_Ca_fluxes__Ca_JSR =
            var_chaste_interface__intracellular_ion_concentrations__Ca_JSR; // millimolar
        const NekDouble var_intracellular_Ca_fluxes__tau_tr =
            0.0005747; // second
        const NekDouble var_intracellular_Ca_fluxes__J_tr =
            (var_intracellular_Ca_fluxes__Ca_NSR -
             var_intracellular_Ca_fluxes__Ca_JSR) /
            var_intracellular_Ca_fluxes__tau_tr; // millimolar_per_second
        const NekDouble var_intracellular_Ca_fluxes__Cai =
            var_chaste_interface__intracellular_ion_concentrations__Cai; // millimolar
        const NekDouble var_intracellular_Ca_fluxes__tau_xfer =
            0.0267; // second
        const NekDouble var_intracellular_Ca_fluxes__Ca_ss =
            var_chaste_interface__intracellular_ion_concentrations__Ca_ss; // millimolar
        const NekDouble var_intracellular_Ca_fluxes__J_xfer =
            (var_intracellular_Ca_fluxes__Ca_ss -
             var_intracellular_Ca_fluxes__Cai) /
            var_intracellular_Ca_fluxes__tau_xfer; // millimolar_per_second
        const NekDouble var_intracellular_Ca_fluxes__k_htrpn_minus =
            0.066; // per_second
        const NekDouble var_intracellular_Ca_fluxes__k_htrpn_plus =
            20000.0; // per_millimolar_second
        const NekDouble var_intracellular_Ca_fluxes__HTRPNCa =
            var_chaste_interface__intracellular_Ca_fluxes__HTRPNCa; // millimolar
        const NekDouble
            var_intracellular_Ca_fluxes__d_HTRPNCa_d_environment__time =
                (var_intracellular_Ca_fluxes__k_htrpn_plus *
                 var_intracellular_Ca_fluxes__Cai *
                 (1.0 - var_intracellular_Ca_fluxes__HTRPNCa)) -
                (var_intracellular_Ca_fluxes__k_htrpn_minus *
                 var_intracellular_Ca_fluxes__HTRPNCa); // 'millimole per litre
                                                        // per second'
        const NekDouble var_intracellular_Ca_fluxes__J_HTRPNCa =
            var_intracellular_Ca_fluxes__d_HTRPNCa_d_environment__time; // millimolar_per_second
        const NekDouble var_intracellular_Ca_fluxes__LTRPN_tot =
            0.07; // dimensionless
        const NekDouble var_intracellular_Ca_fluxes__LTRPNCa =
            var_chaste_interface__intracellular_Ca_fluxes__LTRPNCa; // millimolar
        const NekDouble var_intracellular_Ca_fluxes__k_ltrpn_minus =
            40.0; // per_second
        const NekDouble var_intracellular_Ca_fluxes__k_ltrpn_plus =
            40000.0; // per_millimolar_second
        const NekDouble
            var_intracellular_Ca_fluxes__d_LTRPNCa_d_environment__time =
                (var_intracellular_Ca_fluxes__k_ltrpn_plus *
                 var_intracellular_Ca_fluxes__Cai *
                 (1.0 - var_intracellular_Ca_fluxes__LTRPNCa)) -
                (var_intracellular_Ca_fluxes__k_ltrpn_minus *
                 var_intracellular_Ca_fluxes__LTRPNCa); // 'millimole per litre
                                                        // per second'
        const NekDouble var_intracellular_Ca_fluxes__J_LTRPNCa =
            var_intracellular_Ca_fluxes__d_LTRPNCa_d_environment__time; // millimolar_per_second
        const NekDouble var_intracellular_Ca_fluxes__HTRPN_tot =
            0.14; // dimensionless
        const NekDouble var_intracellular_Ca_fluxes__J_trpn =
            (var_intracellular_Ca_fluxes__HTRPN_tot *
             var_intracellular_Ca_fluxes__J_HTRPNCa) +
            (var_intracellular_Ca_fluxes__LTRPN_tot *
             var_intracellular_Ca_fluxes__J_LTRPNCa); // millimolar_per_second
        const NekDouble var_intracellular_ion_concentrations__Cai =
            var_chaste_interface__intracellular_ion_concentrations__Cai; // millimolar
        const NekDouble var_intracellular_ion_concentrations__Ca_ss =
            var_chaste_interface__intracellular_ion_concentrations__Ca_ss; // millimolar
        const NekDouble var_intracellular_ion_concentrations__Ca_JSR =
            var_chaste_interface__intracellular_ion_concentrations__Ca_JSR; // millimolar
        const NekDouble var_intracellular_ion_concentrations__A_cap =
            0.0001534; // cm2
        const NekDouble var_intracellular_ion_concentrations__V_myo =
            2.584e-05; // micro_litre
        const NekDouble var_intracellular_ion_concentrations__V_JSR =
            1.6e-07; // micro_litre
        const NekDouble var_intracellular_ion_concentrations__V_NSR =
            2.1e-06; // micro_litre
        const NekDouble var_intracellular_ion_concentrations__V_SS =
            1.2e-09; // micro_litre
        const NekDouble var_intracellular_ion_concentrations__K_mCMDN =
            0.00238; // millimolar
        const NekDouble var_intracellular_ion_concentrations__K_mEGTA =
            0.00015; // millimolar
        const NekDouble var_intracellular_ion_concentrations__K_mCSQN =
            0.8; // millimolar
        const NekDouble var_intracellular_ion_concentrations__CMDN_tot =
            0.05; // millimolar
        const NekDouble var_intracellular_ion_concentrations__EGTA_tot =
            0.0; // millimolar
        const NekDouble var_intracellular_ion_concentrations__CSQN_tot =
            15.0; // millimolar
        const NekDouble var_intracellular_ion_concentrations__beta_i =
            1.0 / (1.0 +
                   ((var_intracellular_ion_concentrations__CMDN_tot *
                     var_intracellular_ion_concentrations__K_mCMDN) /
                    pow(var_intracellular_ion_concentrations__K_mCMDN +
                            var_intracellular_ion_concentrations__Cai,
                        2.0)) +
                   ((var_intracellular_ion_concentrations__EGTA_tot *
                     var_intracellular_ion_concentrations__K_mEGTA) /
                    pow(var_intracellular_ion_concentrations__K_mEGTA +
                            var_intracellular_ion_concentrations__Cai,
                        2.0))); // dimensionless
        const NekDouble var_intracellular_ion_concentrations__beta_SS =
            1.0 / (1.0 +
                   ((var_intracellular_ion_concentrations__CMDN_tot *
                     var_intracellular_ion_concentrations__K_mCMDN) /
                    pow(var_intracellular_ion_concentrations__K_mCMDN +
                            var_intracellular_ion_concentrations__Ca_ss,
                        2.0)) +
                   ((var_intracellular_ion_concentrations__EGTA_tot *
                     var_intracellular_ion_concentrations__K_mEGTA) /
                    pow(var_intracellular_ion_concentrations__K_mEGTA +
                            var_intracellular_ion_concentrations__Ca_ss,
                        2.0))); // dimensionless
        const NekDouble var_intracellular_ion_concentrations__beta_JSR =
            1.0 / (1.0 + ((var_intracellular_ion_concentrations__CSQN_tot *
                           var_intracellular_ion_concentrations__K_mCSQN) /
                          pow(var_intracellular_ion_concentrations__K_mCSQN +
                                  var_intracellular_ion_concentrations__Ca_JSR,
                              2.0))); // dimensionless
        const NekDouble var_intracellular_ion_concentrations__F =
            var_membrane__F; // coulomb_per_millimole
        const NekDouble var_intracellular_ion_concentrations__i_Na =
            var_fast_sodium_current__i_Na; // microA_per_microF
        const NekDouble var_intracellular_ion_concentrations__i_Ca =
            var_L_type_Ca_current__i_Ca; // microA_per_microF
        const NekDouble var_intracellular_ion_concentrations__i_Na_b =
            var_sodium_background_current__i_Na_b; // microA_per_microF
        const NekDouble var_intracellular_ion_concentrations__i_NaCa =
            var_Na_Ca_exchanger__i_NaCa; // microA_per_microF
        const NekDouble var_intracellular_ion_concentrations__i_NaK =
            var_sodium_potassium_pump__i_NaK; // microA_per_microF
        const NekDouble var_intracellular_ion_concentrations__i_Ca_K =
            var_L_type_Ca_current__i_Ca_K; // microA_per_microF
        const NekDouble var_intracellular_ion_concentrations__i_Kr =
            var_rapid_activating_delayed_rectifiyer_K_current__i_Kr; // microA_per_microF
        const NekDouble var_intracellular_ion_concentrations__i_Ks =
            var_slow_activating_delayed_rectifiyer_K_current__i_Ks; // microA_per_microF
        const NekDouble var_intracellular_ion_concentrations__i_K1 =
            var_time_independent_potassium_current__i_K1; // microA_per_microF
        const NekDouble var_intracellular_ion_concentrations__i_Kp =
            var_plateau_potassium_current__i_Kp; // microA_per_microF
        const NekDouble var_intracellular_ion_concentrations__i_to1 =
            var_transient_outward_potassium_current__i_to1; // microA_per_microF
        const NekDouble var_intracellular_ion_concentrations__i_p_Ca =
            var_sarcolemmal_calcium_pump__i_p_Ca; // microA_per_microF
        const NekDouble var_intracellular_ion_concentrations__i_Ca_b =
            var_calcium_background_current__i_Ca_b; // microA_per_microF
        const NekDouble var_intracellular_ion_concentrations__J_up =
            var_SERCA2a_pump__J_up; // millimolar_per_second
        const NekDouble var_intracellular_ion_concentrations__J_rel =
            var_RyR_channel__J_rel; // millimolar_per_second
        const NekDouble var_intracellular_ion_concentrations__J_xfer =
            var_intracellular_Ca_fluxes__J_xfer; // millimolar_per_second
        const NekDouble var_intracellular_ion_concentrations__J_trpn =
            var_intracellular_Ca_fluxes__J_trpn; // millimolar_per_second
        const NekDouble var_intracellular_ion_concentrations__J_tr =
            var_intracellular_Ca_fluxes__J_tr; // millimolar_per_second
        const NekDouble
            var_intracellular_ion_concentrations__d_Nai_d_environment__time =
                ((-0.0) *
                 (var_intracellular_ion_concentrations__i_Na +
                  var_intracellular_ion_concentrations__i_Na_b +
                  (var_intracellular_ion_concentrations__i_NaCa * 3.0) +
                  (var_intracellular_ion_concentrations__i_NaK * 3.0)) *
                 var_intracellular_ion_concentrations__A_cap * 1.0) /
                (var_intracellular_ion_concentrations__V_myo *
                 var_intracellular_ion_concentrations__F); // 'millimole per
                                                           // litre per second'
        const NekDouble
            var_intracellular_ion_concentrations__d_Cai_d_environment__time =
                var_intracellular_ion_concentrations__beta_i *
                ((var_intracellular_ion_concentrations__J_xfer -
                  (var_intracellular_ion_concentrations__J_up +
                   var_intracellular_ion_concentrations__J_trpn)) +
                 ((((2.0 * var_intracellular_ion_concentrations__i_NaCa) -
                    (var_intracellular_ion_concentrations__i_p_Ca +
                     var_intracellular_ion_concentrations__i_Ca_b)) *
                   var_intracellular_ion_concentrations__A_cap * 1.0) /
                  (2.0 * var_intracellular_ion_concentrations__V_myo *
                   var_intracellular_ion_concentrations__F))); // 'millimole per
                                                               // litre per
                                                               // second'
        const NekDouble
            var_intracellular_ion_concentrations__d_Ki_d_environment__time =
                ((-0.0) *
                 (var_intracellular_ion_concentrations__i_Ca_K +
                  var_intracellular_ion_concentrations__i_Kr +
                  var_intracellular_ion_concentrations__i_Ks +
                  var_intracellular_ion_concentrations__i_K1 +
                  var_intracellular_ion_concentrations__i_Kp +
                  var_intracellular_ion_concentrations__i_to1 +
                  (var_intracellular_ion_concentrations__i_NaK * (-2.0))) *
                 var_intracellular_ion_concentrations__A_cap * 1.0) /
                (var_intracellular_ion_concentrations__V_myo *
                 var_intracellular_ion_concentrations__F); // 'millimole per
                                                           // litre per second'
        const NekDouble
            var_intracellular_ion_concentrations__d_Ca_ss_d_environment__time =
                var_intracellular_ion_concentrations__beta_SS *
                ((((var_intracellular_ion_concentrations__J_rel *
                    var_intracellular_ion_concentrations__V_JSR) /
                   var_intracellular_ion_concentrations__V_SS) -
                  ((var_intracellular_ion_concentrations__J_xfer *
                    var_intracellular_ion_concentrations__V_myo) /
                   var_intracellular_ion_concentrations__V_SS)) -
                 ((var_intracellular_ion_concentrations__i_Ca *
                   var_intracellular_ion_concentrations__A_cap * 1.0) /
                  (2.0 * var_intracellular_ion_concentrations__V_SS *
                   var_intracellular_ion_concentrations__F))); // 'millimole per
                                                               // litre per
                                                               // second'
        const NekDouble
            var_intracellular_ion_concentrations__d_Ca_JSR_d_environment__time =
                var_intracellular_ion_concentrations__beta_JSR *
                (var_intracellular_ion_concentrations__J_tr -
                 var_intracellular_ion_concentrations__J_rel); // 'millimole per
                                                               // litre per
                                                               // second'
        const NekDouble
            var_intracellular_ion_concentrations__d_Ca_NSR_d_environment__time =
                ((var_intracellular_ion_concentrations__J_up *
                  var_intracellular_ion_concentrations__V_myo) /
                 var_intracellular_ion_concentrations__V_NSR) -
                ((var_intracellular_ion_concentrations__J_tr *
                  var_intracellular_ion_concentrations__V_JSR) /
                 var_intracellular_ion_concentrations__V_NSR); // 'millimole per
                                                               // litre per
                                                               // second'
        const NekDouble
            var_chaste_interface__fast_sodium_current_m_gate__d_m_d_environment__time_converter =
                var_fast_sodium_current__fast_sodium_current_m_gate__d_m_d_environment__time; // per_second
        const NekDouble
            var_chaste_interface__fast_sodium_current_m_gate__d_m_d_environment__time =
                0.001 *
                var_chaste_interface__fast_sodium_current_m_gate__d_m_d_environment__time_converter; // 'per millisecond'
        const NekDouble
            var_chaste_interface__fast_sodium_current_h_gate__d_h_d_environment__time_converter =
                var_fast_sodium_current__fast_sodium_current_h_gate__d_h_d_environment__time; // per_second
        const NekDouble
            var_chaste_interface__fast_sodium_current_h_gate__d_h_d_environment__time =
                0.001 *
                var_chaste_interface__fast_sodium_current_h_gate__d_h_d_environment__time_converter; // 'per millisecond'
        const NekDouble
            var_chaste_interface__fast_sodium_current_j_gate__d_j_d_environment__time_converter =
                var_fast_sodium_current__fast_sodium_current_j_gate__d_j_d_environment__time; // per_second
        const NekDouble
            var_chaste_interface__fast_sodium_current_j_gate__d_j_d_environment__time =
                0.001 *
                var_chaste_interface__fast_sodium_current_j_gate__d_j_d_environment__time_converter; // 'per millisecond'
        const NekDouble
            var_chaste_interface__rapid_activating_delayed_rectifiyer_K_current_X_kr_gate__d_X_kr_d_environment__time_converter =
                var_rapid_activating_delayed_rectifiyer_K_current__rapid_activating_delayed_rectifiyer_K_current_X_kr_gate__d_X_kr_d_environment__time; // per_second
        const NekDouble
            var_chaste_interface__rapid_activating_delayed_rectifiyer_K_current_X_kr_gate__d_X_kr_d_environment__time =
                0.001 *
                var_chaste_interface__rapid_activating_delayed_rectifiyer_K_current_X_kr_gate__d_X_kr_d_environment__time_converter; // 'per millisecond'
        const NekDouble
            var_chaste_interface__slow_activating_delayed_rectifiyer_K_current_X_ks_gate__d_X_ks_d_environment__time_converter =
                var_slow_activating_delayed_rectifiyer_K_current__slow_activating_delayed_rectifiyer_K_current_X_ks_gate__d_X_ks_d_environment__time; // per_second
        const NekDouble
            var_chaste_interface__slow_activating_delayed_rectifiyer_K_current_X_ks_gate__d_X_ks_d_environment__time =
                0.001 *
                var_chaste_interface__slow_activating_delayed_rectifiyer_K_current_X_ks_gate__d_X_ks_d_environment__time_converter; // 'per millisecond'
        const NekDouble
            var_chaste_interface__transient_outward_potassium_current_X_to1_gate__d_X_to1_d_environment__time_converter =
                var_transient_outward_potassium_current__transient_outward_potassium_current_X_to1_gate__d_X_to1_d_environment__time; // per_second
        const NekDouble
            var_chaste_interface__transient_outward_potassium_current_X_to1_gate__d_X_to1_d_environment__time =
                0.001 *
                var_chaste_interface__transient_outward_potassium_current_X_to1_gate__d_X_to1_d_environment__time_converter; // 'per millisecond'
        const NekDouble
            var_chaste_interface__transient_outward_potassium_current_Y_to1_gate__d_Y_to1_d_environment__time_converter =
                var_transient_outward_potassium_current__transient_outward_potassium_current_Y_to1_gate__d_Y_to1_d_environment__time; // per_second
        const NekDouble
            var_chaste_interface__transient_outward_potassium_current_Y_to1_gate__d_Y_to1_d_environment__time =
                0.001 *
                var_chaste_interface__transient_outward_potassium_current_Y_to1_gate__d_Y_to1_d_environment__time_converter; // 'per millisecond'
        const NekDouble
            var_chaste_interface__L_type_Ca_current__d_O_d_environment__time_converter =
                var_L_type_Ca_current__d_O_d_environment__time; // per_second
        const NekDouble
            var_chaste_interface__L_type_Ca_current__d_O_d_environment__time =
                0.001 *
                var_chaste_interface__L_type_Ca_current__d_O_d_environment__time_converter; // 'per millisecond'
        const NekDouble
            var_chaste_interface__L_type_Ca_current__d_O_Ca_d_environment__time_converter =
                var_L_type_Ca_current__d_O_Ca_d_environment__time; // per_second
        const NekDouble
            var_chaste_interface__L_type_Ca_current__d_O_Ca_d_environment__time =
                0.001 *
                var_chaste_interface__L_type_Ca_current__d_O_Ca_d_environment__time_converter; // 'per millisecond'
        const NekDouble
            var_chaste_interface__L_type_Ca_current__d_C0_d_environment__time_converter =
                var_L_type_Ca_current__d_C0_d_environment__time; // per_second
        const NekDouble
            var_chaste_interface__L_type_Ca_current__d_C0_d_environment__time =
                0.001 *
                var_chaste_interface__L_type_Ca_current__d_C0_d_environment__time_converter; // 'per millisecond'
        const NekDouble
            var_chaste_interface__L_type_Ca_current__d_C1_d_environment__time_converter =
                var_L_type_Ca_current__d_C1_d_environment__time; // per_second
        const NekDouble
            var_chaste_interface__L_type_Ca_current__d_C1_d_environment__time =
                0.001 *
                var_chaste_interface__L_type_Ca_current__d_C1_d_environment__time_converter; // 'per millisecond'
        const NekDouble
            var_chaste_interface__L_type_Ca_current__d_C2_d_environment__time_converter =
                var_L_type_Ca_current__d_C2_d_environment__time; // per_second
        const NekDouble
            var_chaste_interface__L_type_Ca_current__d_C2_d_environment__time =
                0.001 *
                var_chaste_interface__L_type_Ca_current__d_C2_d_environment__time_converter; // 'per millisecond'
        const NekDouble
            var_chaste_interface__L_type_Ca_current__d_C3_d_environment__time_converter =
                var_L_type_Ca_current__d_C3_d_environment__time; // per_second
        const NekDouble
            var_chaste_interface__L_type_Ca_current__d_C3_d_environment__time =
                0.001 *
                var_chaste_interface__L_type_Ca_current__d_C3_d_environment__time_converter; // 'per millisecond'
        const NekDouble
            var_chaste_interface__L_type_Ca_current__d_C4_d_environment__time_converter =
                var_L_type_Ca_current__d_C4_d_environment__time; // per_second
        const NekDouble
            var_chaste_interface__L_type_Ca_current__d_C4_d_environment__time =
                0.001 *
                var_chaste_interface__L_type_Ca_current__d_C4_d_environment__time_converter; // 'per millisecond'
        const NekDouble
            var_chaste_interface__L_type_Ca_current__d_C_Ca0_d_environment__time_converter =
                var_L_type_Ca_current__d_C_Ca0_d_environment__time; // per_second
        const NekDouble
            var_chaste_interface__L_type_Ca_current__d_C_Ca0_d_environment__time =
                0.001 *
                var_chaste_interface__L_type_Ca_current__d_C_Ca0_d_environment__time_converter; // 'per millisecond'
        const NekDouble
            var_chaste_interface__L_type_Ca_current__d_C_Ca1_d_environment__time_converter =
                var_L_type_Ca_current__d_C_Ca1_d_environment__time; // per_second
        const NekDouble
            var_chaste_interface__L_type_Ca_current__d_C_Ca1_d_environment__time =
                0.001 *
                var_chaste_interface__L_type_Ca_current__d_C_Ca1_d_environment__time_converter; // 'per millisecond'
        const NekDouble
            var_chaste_interface__L_type_Ca_current__d_C_Ca2_d_environment__time_converter =
                var_L_type_Ca_current__d_C_Ca2_d_environment__time; // per_second
        const NekDouble
            var_chaste_interface__L_type_Ca_current__d_C_Ca2_d_environment__time =
                0.001 *
                var_chaste_interface__L_type_Ca_current__d_C_Ca2_d_environment__time_converter; // 'per millisecond'
        const NekDouble
            var_chaste_interface__L_type_Ca_current__d_C_Ca3_d_environment__time_converter =
                var_L_type_Ca_current__d_C_Ca3_d_environment__time; // per_second
        const NekDouble
            var_chaste_interface__L_type_Ca_current__d_C_Ca3_d_environment__time =
                0.001 *
                var_chaste_interface__L_type_Ca_current__d_C_Ca3_d_environment__time_converter; // 'per millisecond'
        const NekDouble
            var_chaste_interface__L_type_Ca_current__d_C_Ca4_d_environment__time_converter =
                var_L_type_Ca_current__d_C_Ca4_d_environment__time; // per_second
        const NekDouble
            var_chaste_interface__L_type_Ca_current__d_C_Ca4_d_environment__time =
                0.001 *
                var_chaste_interface__L_type_Ca_current__d_C_Ca4_d_environment__time_converter; // 'per millisecond'
        const NekDouble
            var_chaste_interface__L_type_Ca_current_y_gate__d_y_d_environment__time_converter =
                var_L_type_Ca_current__L_type_Ca_current_y_gate__d_y_d_environment__time; // per_second
        const NekDouble
            var_chaste_interface__L_type_Ca_current_y_gate__d_y_d_environment__time =
                0.001 *
                var_chaste_interface__L_type_Ca_current_y_gate__d_y_d_environment__time_converter; // 'per millisecond'
        const NekDouble
            var_chaste_interface__RyR_channel__d_P_O1_d_environment__time_converter =
                var_RyR_channel__d_P_O1_d_environment__time; // per_second
        const NekDouble var_chaste_interface__RyR_channel__d_P_O1_d_environment__time =
            0.001 *
            var_chaste_interface__RyR_channel__d_P_O1_d_environment__time_converter; // 'per millisecond'
        const NekDouble
            var_chaste_interface__RyR_channel__d_P_O2_d_environment__time_converter =
                var_RyR_channel__d_P_O2_d_environment__time; // per_second
        const NekDouble var_chaste_interface__RyR_channel__d_P_O2_d_environment__time =
            0.001 *
            var_chaste_interface__RyR_channel__d_P_O2_d_environment__time_converter; // 'per millisecond'
        const NekDouble
            var_chaste_interface__RyR_channel__d_P_C1_d_environment__time_converter =
                var_RyR_channel__d_P_C1_d_environment__time; // per_second
        const NekDouble var_chaste_interface__RyR_channel__d_P_C1_d_environment__time =
            0.001 *
            var_chaste_interface__RyR_channel__d_P_C1_d_environment__time_converter; // 'per millisecond'
        const NekDouble
            var_chaste_interface__RyR_channel__d_P_C2_d_environment__time_converter =
                var_RyR_channel__d_P_C2_d_environment__time; // per_second
        const NekDouble var_chaste_interface__RyR_channel__d_P_C2_d_environment__time =
            0.001 *
            var_chaste_interface__RyR_channel__d_P_C2_d_environment__time_converter; // 'per millisecond'
        const NekDouble
            var_chaste_interface__intracellular_Ca_fluxes__d_HTRPNCa_d_environment__time_converter =
                var_intracellular_Ca_fluxes__d_HTRPNCa_d_environment__time; // ___units_89
        const NekDouble
            var_chaste_interface__intracellular_Ca_fluxes__d_HTRPNCa_d_environment__time =
                0.001 *
                var_chaste_interface__intracellular_Ca_fluxes__d_HTRPNCa_d_environment__time_converter; // 'millimolar per millisecond'
        const NekDouble
            var_chaste_interface__intracellular_Ca_fluxes__d_LTRPNCa_d_environment__time_converter =
                var_intracellular_Ca_fluxes__d_LTRPNCa_d_environment__time; // millimole_per_litre_per_second
        const NekDouble
            var_chaste_interface__intracellular_Ca_fluxes__d_LTRPNCa_d_environment__time =
                0.001 *
                var_chaste_interface__intracellular_Ca_fluxes__d_LTRPNCa_d_environment__time_converter; // 'millimolar per millisecond'
        const NekDouble
            var_chaste_interface__intracellular_ion_concentrations__d_Nai_d_environment__time_converter =
                var_intracellular_ion_concentrations__d_Nai_d_environment__time; // millimole_per_litre_per_second
        const NekDouble
            var_chaste_interface__intracellular_ion_concentrations__d_Nai_d_environment__time =
                0.001 *
                var_chaste_interface__intracellular_ion_concentrations__d_Nai_d_environment__time_converter; // 'millimolar per millisecond'
        const NekDouble
            var_chaste_interface__intracellular_ion_concentrations__d_Cai_d_environment__time_converter =
                var_intracellular_ion_concentrations__d_Cai_d_environment__time; // millimole_per_litre_per_second
        const NekDouble
            var_chaste_interface__intracellular_ion_concentrations__d_Cai_d_environment__time =
                0.001 *
                var_chaste_interface__intracellular_ion_concentrations__d_Cai_d_environment__time_converter; // 'millimolar per millisecond'
        const NekDouble
            var_chaste_interface__intracellular_ion_concentrations__d_Ki_d_environment__time_converter =
                var_intracellular_ion_concentrations__d_Ki_d_environment__time; // millimole_per_litre_per_second
        const NekDouble
            var_chaste_interface__intracellular_ion_concentrations__d_Ki_d_environment__time =
                0.001 *
                var_chaste_interface__intracellular_ion_concentrations__d_Ki_d_environment__time_converter; // 'millimolar per millisecond'
        const NekDouble
            var_chaste_interface__intracellular_ion_concentrations__d_Ca_ss_d_environment__time_converter =
                var_intracellular_ion_concentrations__d_Ca_ss_d_environment__time; // millimole_per_litre_per_second
        const NekDouble
            var_chaste_interface__intracellular_ion_concentrations__d_Ca_ss_d_environment__time =
                0.001 *
                var_chaste_interface__intracellular_ion_concentrations__d_Ca_ss_d_environment__time_converter; // 'millimolar per millisecond'
        const NekDouble
            var_chaste_interface__intracellular_ion_concentrations__d_Ca_JSR_d_environment__time_converter =
                var_intracellular_ion_concentrations__d_Ca_JSR_d_environment__time; // millimole_per_litre_per_second
        const NekDouble
            var_chaste_interface__intracellular_ion_concentrations__d_Ca_JSR_d_environment__time =
                0.001 *
                var_chaste_interface__intracellular_ion_concentrations__d_Ca_JSR_d_environment__time_converter; // 'millimolar per millisecond'
        const NekDouble
            var_chaste_interface__intracellular_ion_concentrations__d_Ca_NSR_d_environment__time_converter =
                var_intracellular_ion_concentrations__d_Ca_NSR_d_environment__time; // millimole_per_litre_per_second
        const NekDouble
            var_chaste_interface__intracellular_ion_concentrations__d_Ca_NSR_d_environment__time =
                0.001 *
                var_chaste_interface__intracellular_ion_concentrations__d_Ca_NSR_d_environment__time_converter; // 'millimolar per millisecond'
        const NekDouble d_dt_chaste_interface__fast_sodium_current_m_gate__m =
            var_chaste_interface__fast_sodium_current_m_gate__d_m_d_environment__time; // 'per millisecond'
        const NekDouble d_dt_chaste_interface__fast_sodium_current_h_gate__h =
            var_chaste_interface__fast_sodium_current_h_gate__d_h_d_environment__time; // 'per millisecond'
        const NekDouble d_dt_chaste_interface__fast_sodium_current_j_gate__j =
            var_chaste_interface__fast_sodium_current_j_gate__d_j_d_environment__time; // 'per millisecond'
        const NekDouble
            d_dt_chaste_interface__rapid_activating_delayed_rectifiyer_K_current_X_kr_gate__X_kr =
                var_chaste_interface__rapid_activating_delayed_rectifiyer_K_current_X_kr_gate__d_X_kr_d_environment__time; // 'per millisecond'
        const NekDouble
            d_dt_chaste_interface__slow_activating_delayed_rectifiyer_K_current_X_ks_gate__X_ks =
                var_chaste_interface__slow_activating_delayed_rectifiyer_K_current_X_ks_gate__d_X_ks_d_environment__time; // 'per millisecond'
        const NekDouble
            d_dt_chaste_interface__transient_outward_potassium_current_X_to1_gate__X_to1 =
                var_chaste_interface__transient_outward_potassium_current_X_to1_gate__d_X_to1_d_environment__time; // 'per millisecond'
        const NekDouble
            d_dt_chaste_interface__transient_outward_potassium_current_Y_to1_gate__Y_to1 =
                var_chaste_interface__transient_outward_potassium_current_Y_to1_gate__d_Y_to1_d_environment__time; // 'per millisecond'
        const NekDouble d_dt_chaste_interface__L_type_Ca_current__O =
            var_chaste_interface__L_type_Ca_current__d_O_d_environment__time; // 'per millisecond'
        const NekDouble d_dt_chaste_interface__L_type_Ca_current__O_Ca =
            var_chaste_interface__L_type_Ca_current__d_O_Ca_d_environment__time; // 'per millisecond'
        const NekDouble d_dt_chaste_interface__L_type_Ca_current__C0 =
            var_chaste_interface__L_type_Ca_current__d_C0_d_environment__time; // 'per millisecond'
        const NekDouble d_dt_chaste_interface__L_type_Ca_current__C1 =
            var_chaste_interface__L_type_Ca_current__d_C1_d_environment__time; // 'per millisecond'
        const NekDouble d_dt_chaste_interface__L_type_Ca_current__C2 =
            var_chaste_interface__L_type_Ca_current__d_C2_d_environment__time; // 'per millisecond'
        const NekDouble d_dt_chaste_interface__L_type_Ca_current__C3 =
            var_chaste_interface__L_type_Ca_current__d_C3_d_environment__time; // 'per millisecond'
        const NekDouble d_dt_chaste_interface__L_type_Ca_current__C4 =
            var_chaste_interface__L_type_Ca_current__d_C4_d_environment__time; // 'per millisecond'
        const NekDouble d_dt_chaste_interface__L_type_Ca_current__C_Ca0 =
            var_chaste_interface__L_type_Ca_current__d_C_Ca0_d_environment__time; // 'per millisecond'
        const NekDouble d_dt_chaste_interface__L_type_Ca_current__C_Ca1 =
            var_chaste_interface__L_type_Ca_current__d_C_Ca1_d_environment__time; // 'per millisecond'
        const NekDouble d_dt_chaste_interface__L_type_Ca_current__C_Ca2 =
            var_chaste_interface__L_type_Ca_current__d_C_Ca2_d_environment__time; // 'per millisecond'
        const NekDouble d_dt_chaste_interface__L_type_Ca_current__C_Ca3 =
            var_chaste_interface__L_type_Ca_current__d_C_Ca3_d_environment__time; // 'per millisecond'
        const NekDouble d_dt_chaste_interface__L_type_Ca_current__C_Ca4 =
            var_chaste_interface__L_type_Ca_current__d_C_Ca4_d_environment__time; // 'per millisecond'
        const NekDouble d_dt_chaste_interface__L_type_Ca_current_y_gate__y =
            var_chaste_interface__L_type_Ca_current_y_gate__d_y_d_environment__time; // 'per millisecond'
        const NekDouble d_dt_chaste_interface__RyR_channel__P_O1 =
            var_chaste_interface__RyR_channel__d_P_O1_d_environment__time; // 'per
                                                                           // millisecond'
        const NekDouble d_dt_chaste_interface__RyR_channel__P_O2 =
            var_chaste_interface__RyR_channel__d_P_O2_d_environment__time; // 'per
                                                                           // millisecond'
        const NekDouble d_dt_chaste_interface__RyR_channel__P_C1 =
            var_chaste_interface__RyR_channel__d_P_C1_d_environment__time; // 'per
                                                                           // millisecond'
        const NekDouble d_dt_chaste_interface__RyR_channel__P_C2 =
            var_chaste_interface__RyR_channel__d_P_C2_d_environment__time; // 'per
                                                                           // millisecond'
        const NekDouble d_dt_chaste_interface__intracellular_Ca_fluxes__HTRPNCa =
            var_chaste_interface__intracellular_Ca_fluxes__d_HTRPNCa_d_environment__time; // 'millimole per litre per millisecond'
        const NekDouble d_dt_chaste_interface__intracellular_Ca_fluxes__LTRPNCa =
            var_chaste_interface__intracellular_Ca_fluxes__d_LTRPNCa_d_environment__time; // 'millimole per litre per millisecond'
        const NekDouble d_dt_chaste_interface__intracellular_ion_concentrations__Nai =
            var_chaste_interface__intracellular_ion_concentrations__d_Nai_d_environment__time; // 'millimole per litre per millisecond'
        const NekDouble d_dt_chaste_interface__intracellular_ion_concentrations__Cai =
            var_chaste_interface__intracellular_ion_concentrations__d_Cai_d_environment__time; // 'millimole per litre per millisecond'
        const NekDouble d_dt_chaste_interface__intracellular_ion_concentrations__Ki =
            var_chaste_interface__intracellular_ion_concentrations__d_Ki_d_environment__time; // 'millimole per litre per millisecond'
        const NekDouble
            d_dt_chaste_interface__intracellular_ion_concentrations__Ca_ss =
                var_chaste_interface__intracellular_ion_concentrations__d_Ca_ss_d_environment__time; // 'millimole per litre per millisecond'
        const NekDouble
            d_dt_chaste_interface__intracellular_ion_concentrations__Ca_JSR =
                var_chaste_interface__intracellular_ion_concentrations__d_Ca_JSR_d_environment__time; // 'millimole per litre per millisecond'
        const NekDouble
            d_dt_chaste_interface__intracellular_ion_concentrations__Ca_NSR =
                var_chaste_interface__intracellular_ion_concentrations__d_Ca_NSR_d_environment__time; // 'millimole per litre per millisecond'
 
        const NekDouble var_membrane__C_sc = 0.001; // microF_per_cm2
        const NekDouble var_membrane__i_Na =
            var_fast_sodium_current__i_Na; // microA_per_microF
        const NekDouble var_membrane__i_Ca =
            var_L_type_Ca_current__i_Ca; // microA_per_microF
        const NekDouble var_membrane__i_Ca_K =
            var_L_type_Ca_current__i_Ca_K; // microA_per_microF
        const NekDouble var_membrane__i_Kr =
            var_rapid_activating_delayed_rectifiyer_K_current__i_Kr; // microA_per_microF
        const NekDouble var_membrane__i_Ks =
            var_slow_activating_delayed_rectifiyer_K_current__i_Ks; // microA_per_microF
        const NekDouble var_membrane__i_to1 =
            var_transient_outward_potassium_current__i_to1; // microA_per_microF
        const NekDouble var_membrane__i_K1 =
            var_time_independent_potassium_current__i_K1; // microA_per_microF
        const NekDouble var_membrane__i_Kp =
            var_plateau_potassium_current__i_Kp; // microA_per_microF
        const NekDouble var_membrane__i_NaCa =
            var_Na_Ca_exchanger__i_NaCa; // microA_per_microF
        const NekDouble var_membrane__i_NaK =
            var_sodium_potassium_pump__i_NaK; // microA_per_microF
        const NekDouble var_membrane__i_p_Ca =
            var_sarcolemmal_calcium_pump__i_p_Ca; // microA_per_microF
        const NekDouble var_membrane__i_Ca_b =
            var_calcium_background_current__i_Ca_b; // microA_per_microF
        const NekDouble var_membrane__i_Na_b =
            var_sodium_background_current__i_Na_b; // microA_per_microF
        const NekDouble var_chaste_interface__membrane__i_Stim = 0.0;
        const NekDouble var_membrane__i_Stim_converter =
            var_chaste_interface__membrane__i_Stim; // uA_per_cm2
        const NekDouble
            var_membrane__chaste_interface__chaste_membrane_capacitance =
                1.0; // uF_per_cm2
        const NekDouble var_membrane__i_Stim =
            var_membrane__i_Stim_converter /
            var_membrane__chaste_interface__chaste_membrane_capacitance; // microA_per_microF
        const NekDouble var_membrane__d_V_d_environment__time =
            ((-1.0) * 1.0 *
             (var_membrane__i_Na + var_membrane__i_Ca + var_membrane__i_Ca_K +
              var_membrane__i_Kr + var_membrane__i_Ks + var_membrane__i_to1 +
              var_membrane__i_K1 + var_membrane__i_Kp + var_membrane__i_NaCa +
              var_membrane__i_NaK + var_membrane__i_p_Ca +
              var_membrane__i_Na_b + var_membrane__i_Ca_b +
              var_membrane__i_Stim)) /
            var_membrane__C_sc; // 'millivolt per second'
        const NekDouble
            var_chaste_interface__membrane__d_V_d_environment__time_converter =
                var_membrane__d_V_d_environment__time; // ___units_1
        const NekDouble var_chaste_interface__membrane__d_V_d_environment__time =
            0.001 *
            var_chaste_interface__membrane__d_V_d_environment__time_converter; // 'millivolt per millisecond'
        d_dt_chaste_interface__membrane__V =
            var_chaste_interface__membrane__d_V_d_environment__time; // 'millivolt
                                                                     // per
                                                                     // millisecond'
        outarray[0][i] = d_dt_chaste_interface__membrane__V;
        outarray[1][i] = d_dt_chaste_interface__fast_sodium_current_m_gate__m;
        outarray[2][i] = d_dt_chaste_interface__fast_sodium_current_h_gate__h;
        outarray[3][i] = d_dt_chaste_interface__fast_sodium_current_j_gate__j;
        outarray[4][i] =
            d_dt_chaste_interface__rapid_activating_delayed_rectifiyer_K_current_X_kr_gate__X_kr;
        outarray[5][i] =
            d_dt_chaste_interface__slow_activating_delayed_rectifiyer_K_current_X_ks_gate__X_ks;
        outarray[6][i] =
            d_dt_chaste_interface__transient_outward_potassium_current_X_to1_gate__X_to1;
        outarray[7][i] =
            d_dt_chaste_interface__transient_outward_potassium_current_Y_to1_gate__Y_to1;
        outarray[8][i]  = d_dt_chaste_interface__L_type_Ca_current__O;
        outarray[9][i]  = d_dt_chaste_interface__L_type_Ca_current__O_Ca;
        outarray[10][i] = d_dt_chaste_interface__L_type_Ca_current__C0;
        outarray[11][i] = d_dt_chaste_interface__L_type_Ca_current__C1;
        outarray[12][i] = d_dt_chaste_interface__L_type_Ca_current__C2;
        outarray[13][i] = d_dt_chaste_interface__L_type_Ca_current__C3;
        outarray[14][i] = d_dt_chaste_interface__L_type_Ca_current__C4;
        outarray[15][i] = d_dt_chaste_interface__L_type_Ca_current__C_Ca0;
        outarray[16][i] = d_dt_chaste_interface__L_type_Ca_current__C_Ca1;
        outarray[17][i] = d_dt_chaste_interface__L_type_Ca_current__C_Ca2;
        outarray[18][i] = d_dt_chaste_interface__L_type_Ca_current__C_Ca3;
        outarray[19][i] = d_dt_chaste_interface__L_type_Ca_current__C_Ca4;
        outarray[20][i] = d_dt_chaste_interface__L_type_Ca_current_y_gate__y;
        outarray[21][i] = d_dt_chaste_interface__RyR_channel__P_O1;
        outarray[22][i] = d_dt_chaste_interface__RyR_channel__P_O2;
        outarray[23][i] = d_dt_chaste_interface__RyR_channel__P_C1;
        outarray[24][i] = d_dt_chaste_interface__RyR_channel__P_C2;
        outarray[25][i] =
            d_dt_chaste_interface__intracellular_Ca_fluxes__HTRPNCa;
        outarray[26][i] =
            d_dt_chaste_interface__intracellular_Ca_fluxes__LTRPNCa;
        outarray[27][i] =
            d_dt_chaste_interface__intracellular_ion_concentrations__Nai;
        outarray[28][i] =
            d_dt_chaste_interface__intracellular_ion_concentrations__Cai;
        outarray[29][i] =
            d_dt_chaste_interface__intracellular_ion_concentrations__Ki;
        outarray[30][i] =
            d_dt_chaste_interface__intracellular_ion_concentrations__Ca_ss;
        outarray[31][i] =
            d_dt_chaste_interface__intracellular_ion_concentrations__Ca_JSR;
        outarray[32][i] =
            d_dt_chaste_interface__intracellular_ion_concentrations__Ca_NSR;
    }
}
 
/**
 *
 */
void Winslow99::v_GenerateSummary(SummaryList &s)
{
    SolverUtils::AddSummaryItem(s, "Cell model", "Winslow99");
}
 
/**
 *
 */
void Winslow99::v_SetInitialConditions()
{
    Vmath::Fill(m_nq, -96.1638, m_cellSol[0], 1);
    Vmath::Fill(m_nq, 0.0328302, m_cellSol[1], 1);
    Vmath::Fill(m_nq, 0.988354, m_cellSol[2], 1);
    Vmath::Fill(m_nq, 0.99254, m_cellSol[3], 1);
    Vmath::Fill(m_nq, 0.51, m_cellSol[4], 1);
    Vmath::Fill(m_nq, 0.264, m_cellSol[5], 1);
    Vmath::Fill(m_nq, 2.63, m_cellSol[6], 1);
    Vmath::Fill(m_nq, 0.99, m_cellSol[7], 1);
    Vmath::Fill(m_nq, 9.84546e-21, m_cellSol[8], 1);
    Vmath::Fill(m_nq, 0.0, m_cellSol[9], 1);
    Vmath::Fill(m_nq, 0.997208, m_cellSol[10], 1);
    Vmath::Fill(m_nq, 6.38897e-5, m_cellSol[11], 1);
    Vmath::Fill(m_nq, 1.535e-9, m_cellSol[12], 1);
    Vmath::Fill(m_nq, 1.63909e-14, m_cellSol[13], 1);
    Vmath::Fill(m_nq, 6.56337e-20, m_cellSol[14], 1);
    Vmath::Fill(m_nq, 0.00272826, m_cellSol[15], 1);
    Vmath::Fill(m_nq, 6.99215e-7, m_cellSol[16], 1);
    Vmath::Fill(m_nq, 6.71989e-11, m_cellSol[17], 1);
    Vmath::Fill(m_nq, 2.87031e-15, m_cellSol[18], 1);
    Vmath::Fill(m_nq, 4.59752e-20, m_cellSol[19], 1);
    Vmath::Fill(m_nq, 0.798, m_cellSol[20], 1);
    Vmath::Fill(m_nq, 0.0, m_cellSol[21], 1);
    Vmath::Fill(m_nq, 0.0, m_cellSol[22], 1);
    Vmath::Fill(m_nq, 0.47, m_cellSol[23], 1);
    Vmath::Fill(m_nq, 0.53, m_cellSol[24], 1);
    Vmath::Fill(m_nq, 0.98, m_cellSol[25], 1);
    Vmath::Fill(m_nq, 0.078, m_cellSol[26], 1);
    Vmath::Fill(m_nq, 10.0, m_cellSol[27], 1);
    Vmath::Fill(m_nq, 0.00008, m_cellSol[28], 1);
    Vmath::Fill(m_nq, 157.8, m_cellSol[29], 1);
    Vmath::Fill(m_nq, 0.00011, m_cellSol[30], 1);
    Vmath::Fill(m_nq, 0.257, m_cellSol[31], 1);
    Vmath::Fill(m_nq, 0.257, m_cellSol[32], 1);
}
} // namespace Nektar